spermine tetrahydrochloride

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Names

[ CAS No. ]:
306-67-2

[ Name ]:
spermine tetrahydrochloride

[Synonym ]:
N,N'-Bis(3-aMinopropyl)-1,4-butanediaMine Tetrahydrochloride
EINECS 206-189-8
N1,N1'-(Butane-1,4-diyl)bis(propane-1,3-diamine) tetrahydrochloride
Spermine tetrahydrochloride
N-(2-Aminoethyl)-N'-(3-aminopropyl)-1,4-butanediamine tetrahydrochloride
1,5,10,14-tetraazoniatetradecane tetrachloride
Additive Screening
Spermine hydrochloride
Geontine Tetrahydrochloride
Spermine tetrahydrochloride 0.1 M
1,4-Butanediamine, N-(2-aminoethyl)-N-(3-aminopropyl)-, hydrochloride (1:4)
Musculamine tetrahydrochloride
MFCD00012914
Neuridine tetrahydrochloride
Spm tetrahydrochloride
Gerontine tetrahydrochloride

Chemical & Physical Properties

[ Density]:
1.01 g/mL at 20 °C

[ Boiling Point ]:
308.4ºC at 760mmHg

[ Melting Point ]:
310-311 °C (dec.)(lit.)

[ Molecular Formula ]:
C10H30Cl4N4

[ Molecular Weight ]:
334.157

[ Flash Point ]:
175.6ºC

[ Exact Mass ]:
332.106812

[ PSA ]:
76.10000

[ LogP ]:
5.03380

[ Appearance of Characters ]:
powder

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
H2O: 1 M at 20 °C, clear, colorless

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
EJ7230000
CHEMICAL NAME :
1,4-Butanediamine, N,N'-bis(3-aminopropyl)-, tetrahydrochloride
CAS REGISTRY NUMBER :
306-67-2
LAST UPDATED :
199701
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C10-H26-N4.4Cl-H
MOLECULAR WEIGHT :
348.24
WISWESSER LINE NOTATION :
Z3M4M3Z 4GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
370 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - other changes

MUTATION DATA

TYPE OF TEST :
DNA adduct
TEST SYSTEM :
Mammal - species unspecified Lymphocyte
DOSE/DURATION :
16700 nmol/L
REFERENCE :
BIPMAA Biopolymers. (John Wiley & Sons, Inc., 605 Third Ave., New York, NY 10158) V.1- 1963- Volume(issue)/page/year: 5,227,1967

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
EJ7230000

[ HS Code ]:
2921290000

Synthetic Route

Precursor & DownStream

Precursor

  • Spermine

DownStream

Customs

[ HS Code ]: 2921290000

[ Summary ]:
2921290000 other acyclic polyamines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

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Related Compounds

  • SPERMINE TETRAHYDROCHLORIDE
  • Spermine tetrahydrochloride
  • thermospermine tetrahydrochloride
  • N1,N12-Diethylspermine tetrahydrochloride
  • N1,N12-dibenzylspermine tetrahydrochloride
  • N1,N11-Diethylnorspermine tetrahydrochloride
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • N-(4,6-difluorobenzo[d]thiazol-2-yl)-N-(2-morpholinoethyl)isoxazole-5-carboxamide hydrochloride
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide