spermine tetrahydrochloride

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Names

[ CAS No. ]:
306-67-2

[ Name ]:
spermine tetrahydrochloride

[Synonym ]:
N,N'-Bis(3-aMinopropyl)-1,4-butanediaMine Tetrahydrochloride
EINECS 206-189-8
N1,N1'-(Butane-1,4-diyl)bis(propane-1,3-diamine) tetrahydrochloride
Spermine tetrahydrochloride
N-(2-Aminoethyl)-N'-(3-aminopropyl)-1,4-butanediamine tetrahydrochloride
1,5,10,14-tetraazoniatetradecane tetrachloride
Additive Screening
Spermine hydrochloride
Geontine Tetrahydrochloride
Spermine tetrahydrochloride 0.1 M
1,4-Butanediamine, N-(2-aminoethyl)-N-(3-aminopropyl)-, hydrochloride (1:4)
Musculamine tetrahydrochloride
MFCD00012914
Neuridine tetrahydrochloride
Spm tetrahydrochloride
Gerontine tetrahydrochloride

Chemical & Physical Properties

[ Density]:
1.01 g/mL at 20 °C

[ Boiling Point ]:
308.4ºC at 760mmHg

[ Melting Point ]:
310-311 °C (dec.)(lit.)

[ Molecular Formula ]:
C₁₀H₃₀Cl₄N₄

[ Molecular Weight ]:
334.157

[ Flash Point ]:
175.6ºC

[ Exact Mass ]:
332.106812

[ PSA ]:
76.10000

[ LogP ]:
5.03380

[ Appearance of Characters ]:
powder

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
H2O: 1 M at 20 °C, clear, colorless

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: EJ7230000

CHEMICAL NAME :: 1,4-Butanediamine, N,N'-bis(3-aminopropyl)-, tetrahydrochloride

CAS REGISTRY NUMBER :: 306-67-2

LAST UPDATED :: 199701

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C10-H26-N4.4Cl-H

MOLECULAR WEIGHT :: 348.24

WISWESSER LINE NOTATION :: Z3M4M3Z 4GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 370 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - other changes

MUTATION DATA

TYPE OF TEST :: DNA adduct

TEST SYSTEM :: Mammal - species unspecified Lymphocyte

DOSE/DURATION :: 16700 nmol/L

REFERENCE :: BIPMAA Biopolymers. (John Wiley & Sons, Inc., 605 Third Ave., New York, NY 10158) V.1- 1963- Volume(issue)/page/year: 5,227,1967

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
EJ7230000

[ HS Code ]:
2921290000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2921290000

[ Summary ]:
2921290000 other acyclic polyamines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

Interaction of myo-inositol hexakisphosphate with biogenic and synthetic polyamines.

Org. Biomol. Chem. 13 , 7500-12, (2015)

Within all the eukaryotic cells myo-inositol phosphates (InsPs) are an important group of biomolecules that are potentially related to signaling functions. The most abundant member of this family in n...

An Extended-gate Type Organic FET Based Biosensor for Detecting Biogenic Amines in Aqueous Solution.

Anal. Sci. 31 , 721-4, (2015)

This study is the first to report on the detection of biogenic amines in an aqueous solution using an organic field-effect transistor (OFET) device with an extended gate electrode modified with a laye...

Effect of Novel Starter Culture on Reduction of Biogenic Amines, Quality Improvement, and Sensory Properties of Doenjang, a Traditional Korean Soybean Fermented Sauce Variety.

J. Food Sci. 80 , M1794-803, (2015)

To select appropriate microorganisms as starter cultures for the reliable and reproducible fermentation of soybean fermented products of Korean Doenjang, various ratios of fungi (Aspergillus oryzae J,...