Desmesterol

Suppliers

Names

[ CAS No. ]:
313-04-2

[ Name ]:
Desmesterol

[Synonym ]:
cholest-5,24-dien-3β-ol
Desmosterol
Cholesta-5,24-dien-3b-ol
Desmesterol
Cholesta-5,24-dien-3-β-ol
3b-Cholesta-5,24-dien-3-ol
EINECS 206-236-2
Cholesta-5,24-dien-3-ol, (3β)-
MFCD00056432
3ß-hydroxy-5,24-cholestadiene
Cholesta-5,24-dien-3β-ol (8CI)
(3β)-Cholesta-5,24-dien-3-ol
(3β,20R)-Cholesta-5,24-dien-3-ol
Cholesta-5,24-dien-3-ol, (3β,20R)-
Cholesta-5,24-dien-3β-ol
5,24-cholestadien-3β-ol

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
483.2±14.0 °C at 760 mmHg

[ Melting Point ]:
121.5ºC

[ Molecular Formula ]:
C₂₇H₄₄O

[ Molecular Weight ]:
384.638

[ Flash Point ]:
209.2±12.4 °C

[ Exact Mass ]:
384.339203

[ PSA ]:
20.23000

[ LogP ]:
9.54

[ Vapour Pressure ]:
0.0±2.8 mmHg at 25°C

[ Index of Refraction ]:
1.536

[ Storage condition ]:
-20°C

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Δ24-3α,6α-dihydroxy-5β-cholestene
desmosterol acetate
[(3β)-Cholesta-5,24-dien-3-yloxy](1,1-dimethylethyl)dimethylsilane
3β-(tetrahydro-2H-pyran-2-yloxy)chol-5-en-24-ol
2-[(3β)-Cholesta-5,24-dien-3-yloxy]tetrahydro-2H-pyran
3β-acetoxy-Δ5-cholenic aldehyde
(3S,8R,9S,10R,13S,14S,16R,E)-17-ethylidene-10,13-dimethyl-3-((tetrahydro-2H-pyran-2-yl)oxy)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-16-ol
2-(((3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((R)-pent-4-en-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl)oxy)tetrahydro-2H-pyran
(3S,8S,9S,10R,13S,14S,16S,17R)-10,13-dimethyl-17-((R)-pent-4-en-2-yl)-3-((tetrahydro-2H-pyran-2-yl)oxy)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-16-ol
3β-[(tetrahydro-2H-pyran-2-yl)oxy]-16α,17α-epoxy-5-pregnen-20-one

DownStream

Chalinasterol
Dihydrocholesterol
25-Hydroxycholesterol
24(S),25-epoxy Cholesterol

Articles

A liquid chromatography-tandem mass spectrometry-based method for the simultaneous determination of hydroxy sterols and bile acids.

J. Chromatogr. A. 1371 , 184-95, (2014)

Recently, hydroxy sterols and bile acids have gained growing interest as they are important regulators of energy homoeostasis and inflammation. The high number of different hydroxy sterols and bile ac...

Sterol Composition in Infant Formulas and Estimated Intake.

J. Agric. Food Chem. 63 , 7245-51, (2015)

Sterol contents in infant formulas (IFs) from the European market were determined, and their intakes by infants between 0 and 6 months were evaluated. Total animal sterols (mg/100 mL) ranged from 1.71...

Analysis of hedgehog signaling in cerebellar granule cell precursors in a conditional Nsdhl allele demonstrates an essential role for cholesterol in postnatal CNS development.

Hum. Mol. Genet. 24 , 2808-25, (2015)

NSDHL is a 3β-hydroxysterol dehydrogenase that is involved in the removal of two C-4 methyl groups in one of the later steps of cholesterol biosynthesis. Mutations in the gene encoding the enzyme are ...

N-[(1-Methyl-1H-pyrazol-4-yl)methyl]cyclopropanamine dihydrochloride
2-(piperidin-4-yloxy)-1H-benzo[d]imidazole hydrochloride
1-(4-Methylpyridin-2-yl)piperidin-3-amine hydrochloride
3-(3-acetyl-1H-indol-1-yl)-1-(4-benzylpiperidin-1-yl)propan-1-one
1-(6-Ethoxypyridazin-3-yl)piperidin-4-amine hydrochloride
3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrrolidine
Ethyl 2-amino-3,4,5-trimethoxybenzoate
1-[(1-Ethyl-3-methyl-1H-pyrazol-4-yl)methyl]-N-(6-phenoxy-3-pyridinyl)-2-piperidinecarboxamide
N-{2-[(4-methoxybenzyl)amino]-2-oxoethyl}-4-phenylpiperazine-1-carboxamide
N-(5-ethyl-3,3-dimethyl-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepin-8-yl)-2,6-dimethoxybenzamide

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