3-Cbz-6-oxa-3-aza-bicyclo[3.1.0]hexane

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Names

[ CAS No. ]:
31865-25-5

[ Name ]:
3-Cbz-6-oxa-3-aza-bicyclo[3.1.0]hexane

[Synonym ]:
1-benzyloxycarbonyl-3,4-epoxypyrrolidine
3-Cbz-6-oxa-3-aza-bicyclo[3.1.0]hexane
3,4-epoxy-1-carbobenzyloxy-pyrrolidine
Benzyl 6-oxa-3-azabicyclo[3.1.0]hexane-3-carboxylate
6-Oxa-3-azabicyclo[3.1.0]hexane-3-carboxylic acid, phenylmethyl ester
N-benzyloxycarbonyl-3,4-epoxy-pyrrolidine
3-Aza-6-oxabicyclo[3.1]hexane-3-carboxylic acid benzyl ester

Chemical & Physical Properties

[ Density]:
1.305±0.06 g/cm3

[ Boiling Point ]:
353.9±42.0 °C at 760 mmHg

[ Molecular Formula ]:
C12H13NO3

[ Molecular Weight ]:
219.236

[ Flash Point ]:
167.8±27.9 °C

[ Exact Mass ]:
219.089539

[ PSA ]:
42.07000

[ LogP ]:
1.32

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.596

[ Water Solubility ]:
Very slightly soluble (0.48 g/L) (25 ºC)

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Benzyl 2,5-dihydro-1H-pyrrole-1-carboxylate
  • MCPBA
  • N-(benzyloxycarbonyl)diallylamine
  • Benzyl chloroformate
  • N-(Benzyloxycarbonyloxy)succinimide

DownStream

  • 6-oxa-3-azabicyclo[3.1.0]hexane
  • (+)-(3R,4R)-1-benzyloxycarbonyl-3,4-dihydroxypyrrolidine
  • benzyl (3S,4S)-3,4-dihydroxypyrrolidine-1-carboxylate

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 3-Boc-6-oxa-3-aza-bicyclo[3.1.0]hexane
  • 4-benzyloxymethyl-3-(4-methylphenylsulfonyl)-1-phenyl-6-oxa-3-aza-bicyclo[3.1.0]hexane
  • (1R,4R,5R)-4-Hydroxymethyl-6-oxa-3-aza-bicyclo[3.1.0]hexan-2-one
  • 3-methyl-3-aza-bicyclo[3.1.0]hexane-2,4-dione
  • 3-AZABICYCLO[3.1.0]HEXANE-2-CARBOXYLIC ACID
  • 3-Azabicyclo[3.1.0]hexane-2,4-dione,1-(1-methylethyl)-,(1R,5R)-(9CI)
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • 2-[2-Amino-5-(2-methoxyphenoxy)-6-methylpyrimidin-4-YL]-5-[(2,5-dimethylphenyl)methoxy]phenol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide