Haloxon
Suppliers
Names
[ CAS No. ]:
321-55-1
[ Name ]:
Haloxon
[Synonym ]:
2-Ethylhexyl 4,4-bis(3-butoxy-3-oxopropyl)-10-ethyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate
di(2-butoxycarbonylethyl)tin S,S'-bis-(2-ethylhexyl thioglycolate)
Di-(2-chlorethyl)-3-chloro-4-methylcoumarin-7-yl-phosphat
8-Oxa-3,5-dithia-4-stannatetradecanoicacid,4,4-bis(3-butoxy-3-oxopropyl)-10-ethyl-7-oxo-,2-ethylhexyl ester
Haloxon
Chemical & Physical Properties
[ Density]:
1.5g/cm3
[ Boiling Point ]:
504.6ºC at 760 mmHg
[ Molecular Formula ]:
C14H14Cl3O6P
[ Molecular Weight ]:
415.59000
[ Flash Point ]:
438.8ºC
[ Exact Mass ]:
413.95900
[ PSA ]:
84.78000
[ LogP ]:
4.75250
[ Index of Refraction ]:
1.561
[ Storage condition ]:
2-8℃
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- GN5250000
- CHEMICAL NAME :
- Coumarin, 3-chloro-7-hydroxy-4-methyl-, bis(2-chloroethyl) phosphate
- CAS REGISTRY NUMBER :
- 321-55-1
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 8
- MOLECULAR FORMULA :
- C14-H14-Cl3-O6-P
- MOLECULAR WEIGHT :
- 415.60
- WISWESSER LINE NOTATION :
- T66 BOVJ DG E1 IOPO&O2GO2G
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 900 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- >6 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - chicken
- DOSE/DURATION :
- >7 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Bird - chicken
- DOSE/DURATION :
- 800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - domestic
- DOSE/DURATION :
- 763 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - food intake (animal) Gastrointestinal - hypermotility, diarrhea
MUTATION DATA
- TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Human Cells - not otherwise specified
- DOSE/DURATION :
- 10 mg/L
- REFERENCE :
- JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76- Volume(issue)/page/year: 10,143,1982 *** REVIEWS *** TOXICOLOGY REVIEW RREVAH Residue Reviews. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1962- Volume(issue)/page/year: 46,1,1973 TOXICOLOGY REVIEW PMDCAY Progress in Medical Chemistry. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1961- Volume(issue)/page/year: 10,85,1974
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302 + H332-H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ RIDADR ]:
NONH for all modes of transport
[ RTECS ]:
GN5250000
[ HS Code ]:
2932209090
Customs
[ HS Code ]: 2932209090
[ Summary ]:
2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
Vet. Hum. Toxicol. 38(3) , 196-9, (1996)
The serum cholinesterase (ChE) isoenzyme in rats shows 6 bands after polyacrylamide gradient gel electrophoresis. The effects of organophosphates (fenthion, chlorpyrifos, diazinon, bromophos, propapho...
Angew. Parasitol. 27(3) , 175-80, (1986)
Cambendazole and tiabendazole at 10(-4) M concentrations caused mortality in both the parasites after 10 min and 20 min, respectively. H. gallinae was killed by 10(-4) M haloxon but A. galli remained ...
Angew. Parasitol. 31(2) , 101-5, (1990)
Cambendazole 10(-4) M significantly reduced the level of glycogen in both the parasites. Lactic acid level was found enhanced. Oxygen consumption was suppressed by 63 and 94% in A. galli and H. gallin...