H-Glu(OtBu)-OtBu.HCl
Suppliers
Names
[ CAS No. ]:
32677-01-3
[ Name ]:
H-Glu(OtBu)-OtBu.HCl
[Synonym ]:
H-Glu(OtBu)-OtBu·HCl
H-Glu(OtBu)-OtBu��HCl
L-glutamic acid di-t-butyl ester hydrochloride
MFCD00058003
Di-tert-butyl L-glutamate hydrochloride (1:1)
L-Glutamic acid, bis(1,1-dimethylethyl) ester, hydrochloride (1:1)
H-Glu(OtBu)-OtBu,HCl
H-L-Glu(OtBu)-OtBu*HCl
L-Glutamic acid di-tert
L-Glutamic Acid di-Tert-Butyl Ester Hydrochloride
Bis(2-methyl-2-propanyl) L-glutamate hydrochloride (1:1)
(S)-Di-tert-butyl 2-aminopentanedioate hydrochloride
H-Glu(OtBu)-OtBu.HCl
L-Glutamic acid di-tert-butylester hydrochloride
Chemical & Physical Properties
[ Density]:
1.02g/cm3
[ Boiling Point ]:
311.1ºC at 760 mmHg
[ Melting Point ]:
60 to 75ºC
[ Molecular Formula ]:
C13H26ClNO4
[ Molecular Weight ]:
295.803
[ Flash Point ]:
78.1ºC
[ Exact Mass ]:
295.155029
[ PSA ]:
78.62000
[ LogP ]:
3.27960
[ Storage condition ]:
−20°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MA0880000
- CHEMICAL NAME :
- L-Glutamic acid, bis(1,1-dimethylethyl)ester, hydrochloride
- CAS REGISTRY NUMBER :
- 32677-01-3
- LAST UPDATED :
- 198703
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C13-H25-N-O4.Cl-H
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 148 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- NTOTDY Neurobehavioral Toxicology and Teratology. (Fayetteville, NY) V.3-8, 1981-86. For publisher information, see NETEEC. Volume(issue)/page/year: 7,275,1985
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 148 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- NTOTDY Neurobehavioral Toxicology and Teratology. (Fayetteville, NY) V.3-8, 1981-86. For publisher information, see NETEEC. Volume(issue)/page/year: 7,275,1985
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
Xi
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
MA0880000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
Int. J. Pept. Protein Res. 40 , 395-400, (1992)
Analogues of [Orn6]-SP6-11 have been synthesized in which the methionyl residue is replaced by glutamine gamma-carboxamide substituted derivatives. These analogues where tested in three in vitro prepa...
Int. J. Pept. Protein Res. 41 , 411-414, (1993)
Analogues of [Orn6]-SP6-11 have been synthesized in which the Met11-NH2 residue is replaced by the alpha, gamma-dimethyl, alpha, gamma-dibenzyl and alpha, gamma-di-tert-butyl esters of glutamic acid. ...
Neurobehav. Toxicol. Teratol. 7 , 275-278, (1985)
Glutamic acid di-tert butyl ester (GTBE) was found to have a pronounced convulsant effect in mice and rats, producing recurrent clonic convulsions combined with postural and respiratory disturbances i...