L-Norleucine

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Names

[ CAS No. ]:
327-57-1

[ Name ]:
L-Norleucine

[Synonym ]:
L-2-Aminohexanoic acid
EINECS 206-321-4
(S)-Norleucine
Norleucine
(S)-2-amino-Hexanoic acid
(S)-(+)-2-Aminohexanoic acid
H-L-NLE-OH
Glycoleucine
H-L-NORLEUCINE
L-Norleucine
(S)-(+)-2-Aminohexanoic acid (S)-2-Aminocaproic acid
(S)-Aminohexanoic acid
(S)-a-Aminocaproic acid
L-2-Amino-hexanoic acid
L-Aminohexanoic acid
Norleucine, L-
(S)-2-Aminohexanoic acid
caprine
H-NLE-OH
H-ACPO(2)-OH
L-2-aminohexanoate
H-AHX(2)-OH
D,L-Norleucine
MFCD00064423
L(+)-Norleucine
(S)-2-aminocaproic acid
N-NORLEUCINE

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
234.0±23.0 °C at 760 mmHg

[ Melting Point ]:
300ºC

[ Molecular Formula ]:
C₆H₁₃NO₂

[ Molecular Weight ]:
131.173

[ Flash Point ]:
95.3±22.6 °C

[ Exact Mass ]:
131.094635

[ PSA ]:
63.32000

[ LogP ]:
0.92

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.465

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RC6308000

CHEMICAL NAME :: Norleucine, L-

CAS REGISTRY NUMBER :: 327-57-1

BEILSTEIN REFERENCE NO. :: 1721750

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C6-H13-N-O2

MOLECULAR WEIGHT :: 131.20

WISWESSER LINE NOTATION :: ZY4&VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Microorganism - not otherwise specified

DOSE/DURATION :: 100 mg/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 12,349,1971

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H317

[ Precautionary Statements ]:
P280

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R43

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
RC6308000

[ HS Code ]:
29224995

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

(3S,5S,6R)-4-(benzyloxycarbonyl)-3-butyl-5,6-diphenyl-2,3,5,6-tetrahydro-4H-1,4-oxazin-2-one
(3S,5S)-2,3,5,6-tetrahydro-3-(3-butenyl)-5-phenyl-N-(benzyloxycarbonyl)-4H-1,4-oxazine-2-one
D,L-Nle(OBn)*HCl
n-acetyl-dl-norleucine
2-amino-(S,Z)-3-hexenoic acid hydrobromide
(3S,5S)-2,3,5,6-tetrahydro-3-(4-bromobutyl)-5-phenyl-N-(benzyloxycarbonyl)-4H-1,4-oxazine-2-one
H-DL-Nle-OH
L-Homopropargylglycine
L-norleucine benzylester

DownStream

H-Nle-OMe.HCl
Z-Nle-OH
Acetamide
Valeraldehyde
N-Boc-L-Norleucine
H-DL-Nle-OH
FOR-NLE-OH
2-FLUORO-2,3,5-TRIACETOXYADENOSINE
Boc-N-Me-Nle-OH
α-Aminoadipic acid

Customs

[ HS Code ]: 2922499990

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

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