5-methyl-2-thiouridine

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Names

[ CAS No. ]:
32738-09-3

[ Name ]:
5-methyl-2-thiouridine

[Synonym ]:
2-Sulfamyl-4-methyl-phenyl-thioharnstoff
5-Methyl-2-thio-uridin
5-methyl-2-thioureido-benzenesulfonamide
5-Methyl-1-pentofuranosyl-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone
4-Methyl-2-sulphamylphenylthiourea
Benzenesulfonamide,2-[(aminothioxomethyl)amino]-5-methyl

Chemical & Physical Properties

[ Density]:
1.63g/cm3

[ Melting Point ]:
216-219 °C

[ Molecular Formula ]:
C10H14N2O5S

[ Molecular Weight ]:
274.29

[ Exact Mass ]:
274.06200

[ PSA ]:
140.06000

[ Index of Refraction ]:
1.703

MSDS

Click to get detail MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2934999090

Precursor & DownStream

Precursor

  • O2',O3',O5'-tribenzoyl-5-methyl-2-thio-uridine
  • 2,3,5-Tri-O-benzoyl-β-D-ribofuranosyl azide

DownStream

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Molecular mechanism of codon recognition by tRNA species with modified uridine in the first position of the anticodon.

Proc. Natl. Acad. Sci. U. S. A. 82 , 4905-4909, (1985)

Proton NMR analyses have been made to elucidate the conformational characteristics of modified nucleotides as found in the first position of the anticodon of tRNA [derivatives of 5-methyl-2-thiouridin...

CD spectra of 5-methyl-2-thiouridine in tRNA-Met-f from an extreme thermophile.

Nucleic Acids Res. 3 , 1703-1713, (1976)

5-Methyl-2-thiouridine (S) in tRNA-Met-f from an extreme thermophile is located in the TpsiC region, replacing T, and has a positive CD band centered at 310 nm. Upon heating, the profiles of the chang...

Stabilizing contributions of sulfur-modified nucleotides: crystal structure of a DNA duplex with 2'-O-[2-(methoxy)ethyl]-2-thiothymidines.

Nucleic Acids Res. 33 , 5297-5307, (2005)

Substitution of oxygen atoms by sulfur at various locations in the nucleic acid framework has led to analogs such as the DNA phosphorothioates and 4'-thio RNA. The phosphorothioates are excellent mimi...


More Articles

Related Compounds

  • 1-(4,6-Dimethyl-1,3-benzothiazol-2-yl)piperidine-4-carboxamide
  • 4-[[2-(Thiomorpholine-4-carbonyl)morpholin-4-yl]methyl]benzonitrile
  • 6-Ethyl-5-fluoro-N-methyl-N-(1-pyrazin-2-ylazetidin-3-yl)pyrimidin-4-amine
  • N-methyl-N-{[1-(6-methylpyrimidin-4-yl)piperidin-4-yl]methyl}-4-(trifluoromethyl)pyridin-2-amine
  • 2-Methyl-4-(pyrrolidin-1-yl)-6-{4-[6-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}pyrimidine
  • 4-[(3,4-Difluorophenyl)methyl]-2-(piperidine-1-carbonyl)morpholine
  • N-{[1-(thiophen-3-yl)cyclopropyl]methyl}furan-3-carboxamide
  • 2-{[1-(4-Methylthiophene-2-carbonyl)pyrrolidin-3-yl]methoxy}pyridine
  • 4-{6-[4-(5-Methyl-1,3,4-thiadiazol-2-yl)piperazin-1-yl]pyridazin-3-yl}morpholine
  • 1-(3-Methylphenyl)-3-[1-(oxan-4-yl)pyrrolidin-3-yl]urea
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