5-methyl-2-thiouridine

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Names

[ CAS No. ]:
32738-09-3

[ Name ]:
5-methyl-2-thiouridine

[Synonym ]:
2-Sulfamyl-4-methyl-phenyl-thioharnstoff
5-Methyl-2-thio-uridin
5-methyl-2-thioureido-benzenesulfonamide
5-Methyl-1-pentofuranosyl-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone
4-Methyl-2-sulphamylphenylthiourea
Benzenesulfonamide,2-[(aminothioxomethyl)amino]-5-methyl

Chemical & Physical Properties

[ Density]:
1.63g/cm3

[ Melting Point ]:
216-219 °C

[ Molecular Formula ]:
C10H14N2O5S

[ Molecular Weight ]:
274.29

[ Exact Mass ]:
274.06200

[ PSA ]:
140.06000

[ Index of Refraction ]:
1.703

MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2934999090

Precursor & DownStream

Precursor

  • O2',O3',O5'-tribenzoyl-5-methyl-2-thio-uridine
  • 2,3,5-Tri-O-benzoyl-β-D-ribofuranosyl azide

DownStream

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Molecular mechanism of codon recognition by tRNA species with modified uridine in the first position of the anticodon.

Proc. Natl. Acad. Sci. U. S. A. 82 , 4905-4909, (1985)

Proton NMR analyses have been made to elucidate the conformational characteristics of modified nucleotides as found in the first position of the anticodon of tRNA [derivatives of 5-methyl-2-thiouridin...

CD spectra of 5-methyl-2-thiouridine in tRNA-Met-f from an extreme thermophile.

Nucleic Acids Res. 3 , 1703-1713, (1976)

5-Methyl-2-thiouridine (S) in tRNA-Met-f from an extreme thermophile is located in the TpsiC region, replacing T, and has a positive CD band centered at 310 nm. Upon heating, the profiles of the chang...

Stabilizing contributions of sulfur-modified nucleotides: crystal structure of a DNA duplex with 2'-O-[2-(methoxy)ethyl]-2-thiothymidines.

Nucleic Acids Res. 33 , 5297-5307, (2005)

Substitution of oxygen atoms by sulfur at various locations in the nucleic acid framework has led to analogs such as the DNA phosphorothioates and 4'-thio RNA. The phosphorothioates are excellent mimi...


More Articles


Related Compounds

  • (2-Ethyl-2-azaspiro[4.4]nonan-7-yl)methanethiol
  • N-(4-sulfamoylphenyl)-6-(1H-1,2,4-triazol-1-yl)pyridazine-3-carboxamide
  • 8-Ethyl-2-methyl-2,8-diazaspiro[4.5]decane
  • 3-(Ethylamino)-4-(thiophen-3-yl)butan-1-ol
  • 4-methyl-N-((1-methyl-4,5,6,7-tetrahydro-1H-indazol-3-yl)methyl)-1,2,3-thiadiazole-5-carboxamide
  • 2-(2,5-dioxopyrrolidin-1-yl)-N-((1-methyl-4,5,6,7-tetrahydro-1H-indazol-3-yl)methyl)acetamide
  • N-((1-methyl-4,5,6,7-tetrahydro-1H-indazol-3-yl)methyl)-3-(phenylthio)propanamide
  • [6-(Difluoromethyl)pyridin-3-YL]boronic acid
  • 2-(Bromomethyl)-6-isopropyl-6-azaspiro[3.4]octane
  • (2-(methylthio)phenyl)(4-((2-phenyl-1H-imidazol-1-yl)methyl)piperidin-1-yl)methanone
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