5-Bromo-2-chloropyrimidine

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Names

[ CAS No. ]:
32779-36-5

[ Name ]:
5-Bromo-2-chloropyrimidine

[Synonym ]:
T6N CNJ BG EE
5-BROMO-2-CHLOROPYRIMIDNE
Pyrimidine, 5-bromo-2-chloro-
2-chloro-5-bromopyrimidine(5-bromo-2-chloropyrimidine)
2C5BP
MAJORIMPURITYIS2,5-DIBROMOPYRIMIDINE
PYRIMIDINE,5-BROMO-2-CHLORO
5-bromo-2-chloro-pyrimidine
MFCD00483232
2-CHLORO-5-BROMOPYRIMIDINE
5-Bromo-2-chloropyrimidine
5-Bromo-2-chloro-1,3-diazine
2,5-bromochloro pyrimidine
2-chloro-5-bromopyridine

Chemical & Physical Properties

[ Density]:
1.9±0.1 g/cm3

[ Boiling Point ]:
291.6±13.0 °C at 760 mmHg

[ Melting Point ]:
76-81 °C(lit.)

[ Molecular Formula ]:
C4H2BrClN2

[ Molecular Weight ]:
193.43

[ Flash Point ]:
130.1±19.8 °C

[ Exact Mass ]:
191.908981

[ PSA ]:
25.78000

[ LogP ]:
1.36

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.588

[ Water Solubility ]:
insoluble

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36/39-S37/39

[ RIDADR ]:
UN 3335

[ WGK Germany ]:
3

[ HS Code ]:
2933599090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 5-Bromo-2-hydroxypyrimidine
  • 5-Bromopyrimidine
  • 5-Bromopyrimidin-2-amine

DownStream

  • 2-(2-Chloro-5-pyrimidinyl)-2-propanol
  • 2,5-Dibromopyrimidine
  • 5-Bromo-N-methylpyrimidin-2-amine
  • tert-Butyl 4-(5-bromopyrimidin-2-yl)piperazine-1-carboxylate
  • 5-Bromo-2-pyrimidinecarbonitrile
  • 5-Bromo-N,N-dimethylpyrimidin-2-amine
  • 5-bromo-1H-pyrimidine-2-thione
  • Methyl 4-((5-bromopyrimidin-2-yl)oxy)benzoate
  • 2-Chloro-5-(4-methoxyphenyl)pyrimidine
  • 5H-(1)Benzopyrano(2,3-b)pyridine

Customs

[ HS Code ]: 2933599090

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Cross-coupling reactions of indium organometallics with 2,5-dihalopyrimidines: synthesis of hyrtinadine A.

Org. Lett. 10(17) , 3745-8, (2008)

The palladium-catalyzed cross-coupling reaction of triorganoindium reagents (R3In) with 5-bromo-2-chloropyrimidine proceeds chemoselectively, in good yields, to give 5-substituted-2-chloropyrimidines ...

Improved synthesis of 2,2'-bipyrimidine.

J. Org. Chem. 67(18) , 6550-2, (2002)

A high-yield synthesis was developed for the preparation of 2,2'-bipyrimidine (1) using the Ullmann coupling of 2-iodopyrimidine. The new procedure was also used for the preparation of 4,4',6,6'-tetra...


More Articles

Related Compounds

  • 4-Amino-5-bromo-2-chloropyrimidine
  • 4-anilino-5-bromo-2-chloropyrimidine
  • 4-Benzyloxy-5-bromo-2-chloropyrimidine
  • 5-Bromo-2-chloropyrimidine-4-carboxylic acid
  • ethyl 5-bromo-2-chloropyrimidine-4-carboxylate
  • 4-(1-Benzothiophen-2-yl)-5-bromo-2-chloropyrimidine