Perfluorooctanoic Acid

Suppliers

Names

[ CAS No. ]:
335-67-1

[ Name ]:
Perfluorooctanoic Acid

[Synonym ]:
A 5717
[14C]-Perfluorooctanoic acid
nPFOA
Eftop EF 201
perfluorocaprylic acid
RARECHEM AL BO 0424
pentadecafluorocaprylic acid
Pentadecafluorooctanoic acid
octanoic acid, pentadecafluoro-
EF 201
Perfluoroctanoic acid
Perfluorooctanoic Acid
EINECS 206-397-9
Perfluoro-n-octanoic acid
PFOA,Perfluorocaprylic acid,Perfluorooctanoic acid
PFOA,Perfluorocaprylic acid
perfluorooctylcarboxylic acid
PFOA
MFCD00004174
Perfluorooctanoic Acid High Grade
Octanoic acid, 2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-pentadecafluoro-
Pentadecafluorooctanoic Acid High Grade
PERFLUOROOCTANOATE
IPC-PFFA-8
Fluorad FC-26
n-Perfluorooctanoic acid
IPC-PFFA-8 HG

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
188.0±0.0 °C at 760 mmHg

[ Melting Point ]:
55-56 °C(lit.)

[ Molecular Formula ]:
C₈HF₁₅O₂

[ Molecular Weight ]:
414.068

[ Flash Point ]:
62.1±25.9 °C

[ Exact Mass ]:
413.973694

[ PSA ]:
37.30000

[ LogP ]:
7.75

[ Vapour Pressure ]:
0.3±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.289

[ Storage condition ]:
2-8°C

[ Stability ]:
Stable. Incompatible with bases, oxidizing agents, reducing agents.

[ Water Solubility ]:
3.4 g/L

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RH0781000

CHEMICAL NAME :: Octanoic acid, pentadecafluoro-

CAS REGISTRY NUMBER :: 335-67-1

BEILSTEIN REFERENCE NO. :: 1809678

LAST UPDATED :: 199710

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C8-H-F15-O2

MOLECULAR WEIGHT :: 414.09

WISWESSER LINE NOTATION :: QVXFFXFFXFFXFFXFFXFFXFFF

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 189 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 42 mg/kg/7D-I

TOXIC EFFECTS :: Liver - changes in liver weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other transferases Biochemical - Metabolism (Intermediary) - lipids including transport

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 84 mg/kg/2W-C

TOXIC EFFECTS :: Liver - changes in liver weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other oxidoreductases

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1092 mg/kg/26W-C

TOXIC EFFECTS :: Liver - changes in liver weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other oxidoreductases

TYPE OF TEST :: DNA damage

MUTATION DATA

TEST SYSTEM :: Rodent - rat

DOSE/DURATION :: 168 mg/kg/2W (Continuous)

REFERENCE :: CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 57,55,1991

Safety Information

[ Symbol ]:

GHS05, GHS07, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302 + H332-H318-H351-H360D-H362-H372

[ Precautionary Statements ]:
P201-P260-P263-P280-P305 + P351 + P338 + P310-P308 + P313

[ Target Organs ]:
Liver

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
C:Corrosive

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S26-S36/37/39-S45-S36/37

[ RIDADR ]:
UN 3261 8/PG 3

[ WGK Germany ]:
2

[ RTECS ]:
RH0781000

[ Packaging Group ]:
III

[ Hazard Class ]:
8

[ HS Code ]:
29159080

Precursor & DownStream

Precursor

Sodium pentadecafluorooctanoate
Perfluorooctyl iodide
sodium heptadecafluorooctanesulphinate
allyl bromide
3-Bromopropyne
Sodium hydroxymethanesulfinate
ALLYL CHLORIDE
phenylpropyne
dec-1-yne
Oct-1-yne

DownStream

METHYL PERFLUOROOCTANOATE
1H-PERFLUOROPENTANE 98
1H-Tridecafluorohexane
Perfluoropentanoic acid
1-HYDRO-PENTADECAFLUOROHEPTANE
Perfluorohexanoic acid
Perfluoroheptanoic acid
Pentadecafluorooctanoyl chloride
Perfluoroheptene-1
perfluorooctanamide

Customs

[ HS Code ]: 2915900090

[ Summary ]:
2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%

Articles

Perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA): emerging contaminants of increasing concern in fish from Lake Varese, Italy.

Environ. Monit. Assess. 187 , 438, (2015)

Perfluoroalkylated substances (PFASs) are highly fluorinated aliphatic compounds with high thermal and chemical stability, used in a range of industrial applications. Extensive screening analyses in b...

Occurrence of perfluorinated alkyl substances in sediment from estuarine and coastal areas of the East China Sea.

Environ. Sci. Pollut. Res. Int. 22(3) , 1662-9, (2015)

Perfluorinated alkyl substances (PFAS) have drawn much attention due to their environmental persistence, ubiquitous existence, and bioaccumulation potential. The occurrence and spatial variation of PF...

Associations between perfluoroalkyl compounds and immune and clinical chemistry parameters in highly exposed bottlenose dolphins (Tursiops truncatus).

Environ. Toxicol. Chem. 32(4) , 736-46, (2013)

Perfluoroalkyl compounds (PFCs) are ubiquitous, persistent chemical contaminants found in the environment, wildlife, and humans. Despite the widespread occurrence of PFCs, little is known about the im...

8H-PERFLUOROOCTANOIC ACID
perfluorooctanoic acid amide
perfluorooctanoic acid chloride
Perfluorooctanoic acid sodium salt
Perfluorooctanoic Acid Methyl Ester
perfluorooctanoic acid ammonium salt
tert-butyl N-(6-chloro-2,5-dimethylpyrimidin-4-yl)carbamate
N-(3-cyclopropanecarbonylpyridin-4-yl)-2,2,2-trifluoroacetamide
tert-butyl N-{5-[1-(aminooxy)-2-methylpropan-2-yl]-4-methyl-1,3-thiazol-2-yl}carbamate
Methyl 2-amino-3-(3-fluoro-4-hydroxy-5-nitrophenyl)propanoate
Tert-butyl 2-amino-3-(3,5-difluoropyridin-4-yl)propanoate
rac-2-{[(3R,4R)-4-hydroxy-1-[(prop-2-en-1-yloxy)carbonyl]pyrrolidin-3-yl](methyl)amino}acetic acid
(2R)-2-{2-amino-N-[(prop-2-en-1-yloxy)carbonyl]acetamido}-3-methylbutanoic acid
4-[Methyl(2-methylpropyl)amino]-2-(trifluoromethyl)cyclohexane-1-carboxylic acid
Benzyl 3-hydroxy-3-(2-methylpropyl)azetidine-1-carboxylate
2-(4-Methyl-1,3-oxazol-2-yl)-1,3-thiazole-5-carboxylic acid

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.