Perfluorooctanoic Acid

Modify Date: 2026-07-01 19:17:31

Perfluorooctanoic Acid Structure
Perfluorooctanoic Acid structure
 Common Name Perfluorooctanoic Acid
CAS Number 335-67-1 Molecular Weight 414.068
Density 1.7±0.1 g/cm3 Boiling Point 188.0±0.0 °C at 760 mmHg
Molecular Formula C8HF15O2 Melting Point 55-56 °C(lit.)
MSDS Chinese USA Flash Point 62.1±25.9 °C
Symbol GHS05 GHS07 GHS08
GHS05, GHS07, GHS08		 Signal Word Danger

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name perfluorooctanoic acid
Synonym More Synonyms

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 1.7±0.1 g/cm3
Boiling Point 188.0±0.0 °C at 760 mmHg
Melting Point 55-56 °C(lit.)
Molecular Formula C8HF15O2
Molecular Weight 414.068
Flash Point 62.1±25.9 °C
Exact Mass 413.973694
PSA 37.30000
LogP 7.75
Vapour Pressure 0.3±0.7 mmHg at 25°C
Index of Refraction 1.289
InChIKey SNGREZUHAYWORS-UHFFFAOYSA-N
SMILES O=C(O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F
Storage condition 2-8°C
Stability Stable. Incompatible with bases, oxidizing agents, reducing agents.
Water Solubility 3.4 g/L

 MSDS

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

 Toxicological Information

This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RH0781000
CHEMICAL NAME :
Octanoic acid, pentadecafluoro-
CAS REGISTRY NUMBER :
335-67-1
BEILSTEIN REFERENCE NO. :
1809678
LAST UPDATED :
199710
DATA ITEMS CITED :
9
MOLECULAR FORMULA :
C8-H-F15-O2
MOLECULAR WEIGHT :
414.09
WISWESSER LINE NOTATION :
QVXFFXFFXFFXFFXFFXFFXFFF

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
189 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
42 mg/kg/7D-I
TOXIC EFFECTS :
Liver - changes in liver weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other transferases Biochemical - Metabolism (Intermediary) - lipids including transport
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
84 mg/kg/2W-C
TOXIC EFFECTS :
Liver - changes in liver weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other oxidoreductases
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1092 mg/kg/26W-C
TOXIC EFFECTS :
Liver - changes in liver weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other oxidoreductases
TYPE OF TEST :
DNA damage

MUTATION DATA

TEST SYSTEM :
Rodent - rat
DOSE/DURATION :
168 mg/kg/2W (Continuous)
REFERENCE :
CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 57,55,1991

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Symbol GHS05 GHS07 GHS08
GHS05, GHS07, GHS08
Signal Word Danger
Hazard Statements H302 + H332-H318-H351-H360D-H362-H372
Precautionary Statements P201-P260-P263-P280-P305 + P351 + P338 + P310-P308 + P313
Target Organs Liver
Personal Protective Equipment Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes C:Corrosive
Risk Phrases R34
Safety Phrases S26-S36/37/39-S45-S36/37
RIDADR UN 3261 8/PG 3
WGK Germany 2
RTECS RH0781000
Packaging Group III
Hazard Class 8
HS Code 29159080

 Customs

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code 2915900090
Summary 2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%

 Articles142

More Articles

This table lists relevant public references with title, journal and publication metadata for this compound.

Perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA): emerging contaminants of increasing concern in fish from Lake Varese, Italy.

Environ. Monit. Assess. 187 , 438, (2015)

Perfluoroalkylated substances (PFASs) are highly fluorinated aliphatic compounds with high thermal and chemical stability, used in a range of industrial applications. Extensive screening analyses in b...

Occurrence of perfluorinated alkyl substances in sediment from estuarine and coastal areas of the East China Sea.

Environ. Sci. Pollut. Res. Int. 22(3) , 1662-9, (2015)

Perfluorinated alkyl substances (PFAS) have drawn much attention due to their environmental persistence, ubiquitous existence, and bioaccumulation potential. The occurrence and spatial variation of PF...

Associations between perfluoroalkyl compounds and immune and clinical chemistry parameters in highly exposed bottlenose dolphins (Tursiops truncatus).

Environ. Toxicol. Chem. 32(4) , 736-46, (2013)

Perfluoroalkyl compounds (PFCs) are ubiquitous, persistent chemical contaminants found in the environment, wildlife, and humans. Despite the widespread occurrence of PFCs, little is known about the im...

 Perfluorooctanoic AcidBioassay

View more

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu...
Source: 824
External Id: CYP273
Name: p53 small molecule agonists, cell-based qHTS assay: qHTS cell viability counter scree...
Source: 824
Target: N/A
External Id: P53600
Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: qHTS ce...
Source: 824
Target: N/A
External Id: P53MS958
Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: Summary
Source: 824
External Id: P53MS482
Name: p53 small molecule agonists, cell-based qHTS assay
Source: 824
External Id: P53344
Name: p53 small molecule agonists, cell-based qHTS assay with human liver microsomes
Source: 824
Target: tumor suppressor p53 [Homo sapiens]
External Id: P53MS233
Name: p53 small molecule agonists, cell-based qHTS assay with human liver microsomes: qHTS ...
Source: 824
Target: N/A
External Id: P53MS837
Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes
Source: 824
Target: tumor suppressor p53 [Homo sapiens]
External Id: P53MS898
Name: Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of Cac...
Source: ChEMBL
Target: Severe acute respiratory syndrome coronavirus 2
External Id: CHEMBL4303805
Name: SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response f...
Source: ChEMBL
Target: Replicase polyprotein 1ab
External Id: CHEMBL4495582
Total 213, Current Page 1 of 22
1
2
3
4
5

 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

A 5717
[14C]-Perfluorooctanoic acid
nPFOA
Eftop EF 201
perfluorocaprylic acid
RARECHEM AL BO 0424
pentadecafluorocaprylic acid
Pentadecafluorooctanoic acid
EF 201
Perfluoroctanoic acid
Perfluorooctanoic Acid
EINECS 206-397-9
Perfluoro-n-octanoic acid
PFOA,Perfluorocaprylic acid,Perfluorooctanoic acid
PFOA,Perfluorocaprylic acid
perfluorooctylcarboxylic acid
PFOA
MFCD00004174
Perfluorooctanoic Acid High Grade
Pentadecafluorooctanoic Acid High Grade
PERFLUOROOCTANOATE
IPC-PFFA-8
Fluorad FC-26
n-Perfluorooctanoic acid
IPC-PFFA-8 HG

 Perfluorooctanoic Acid | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the CAS number of perfluorooctanoic acid?
A: CAS number of perfluorooctanoic acid is 335-67-1.
Q: What is the polar surface area (PSA) of perfluorooctanoic acid?
A: Polar surface area (PSA) of perfluorooctanoic acid is 37.30000.
Q: What are the storage conditions for perfluorooctanoic acid?
A: Storage conditions for perfluorooctanoic acid: 2-8°C.
Q: What is the English name of perfluorooctanoic acid?
A: The English name of perfluorooctanoic acid is perfluorooctanoic acid.
Q: What are the upstream materials of perfluorooctanoic acid?
A: Related upstream materials(CAS) of perfluorooctanoic acid: 335-95-5;507-63-1;68555-67-9;106-95-6;106-96-7;149-44-0;107-05-1;673-32-5;764-93-2;629-05-0.
Q: What is the molecular weight of perfluorooctanoic acid?
A: Molecular weight of perfluorooctanoic acid is 414.068.
Q: What is the InChIKey of perfluorooctanoic acid?
A: InChIKey of perfluorooctanoic acid is SNGREZUHAYWORS-UHFFFAOYSA-N.
Q: What is the boiling point of perfluorooctanoic acid?
A: Boiling point of perfluorooctanoic acid is 188.0±0.0 °C at 760 mmHg.
Q: What is the safety information for perfluorooctanoic acid?
A: Safety information for perfluorooctanoic acid: S26-S36/37/39-S45-S36/37.
Q: What is the SMILES notation of perfluorooctanoic acid?
A: SMILES notation of perfluorooctanoic acid is O=C(O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F.

 Perfluorooctanoic Acidfactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
Henan Tianfu Chemical Co., Ltd.
Zhongshan Xingrui Chemical Co. , Ltd.
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here

Get all suppliers and price by the below link:

Perfluorooctanoic Acid suppliers

Perfluorooctanoic Acid price

Related Compounds: More...
Piperidin-2-ylmethanethiol
85657-12-1
[(Dimethyl-1,3-thiazol-5-yl)methyl](methyl)amine
1267349-64-3
(R)-N-(1-(4-chloromethylphenyl)ethyl)acetamide
223514-71-4
3,8-Diazabicyclo[3.2.1]octane-2,4-dione
5626-62-0
3-Chlorophenyl pivalate
1260665-63-1
(+/-)cis-3-Hydroxyisonipecotic acid
1932266-65-3
(3E)-4-(3-Hydroxynaphthalen-2-YL)-2-oxobut-3-enoic acid
613-41-2
2-Pyrrolidineacetonitrile, 5-thioxo-, (S)
80980-93-4
5-Methyl-4-propylpyrrolidin-2-one
90204-50-5
3,4,5,6-Tetrahydro-N-hydroxy-4-methyl-2H-azepin-7-amine
116570-50-4
Chemsrc provides Perfluorooctanoic Acid(CAS#:335-67-1) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Perfluorooctanoic Acid are included as well.>> amp version: Perfluorooctanoic Acid

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2026 ChemSrc All Rights Reserved