Gonadorelin

Suppliers

Names

[ Name ]:
Gonadorelin

[Synonym ]:
UNII:9O7312W37G
LRF
GONADERELIN
5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosylglycyl-L-leucyl-N-(diaminomethylidene)-L-ornithyl-L-prolylglycinamide
glycinamide, 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosylglycyl-L-leucyl-N-(diaminomethylene)-L-ornithyl-L-prolyl-
Glycinamide, 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosylglycyl-L-leucyl-L-arginyl-L-prolyl-
LH-RH ACETATE
pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2
LHRH,HUMAN
(pyroglutamic acid)-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2
Gonadorelin
Glp-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2
ginadoliberin
GRH
5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosylglycyl-L-leucyl-L-arginyl-L-prolylglycinamide
luteinizing hormone-releasing hormone isoform I
human gonadotropin-releasing hormone I
Pyr-HWSYGLRPG-NH2
EINECS 251-553-1

Chemical & Physical Properties

[ Density]:
1.54

[ Molecular Formula ]:
C₅₅H₇₅N₁₇O₁₃

[ Molecular Weight ]:
1182.290

[ Exact Mass ]:
1181.572998

[ PSA ]:
472.13000

[ LogP ]:
-2.53

[ Index of Refraction ]:
1.713

Safety Information

[ HS Code ]:
2942000000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Z-ARG(NO2)-OH
Nα-Benzyloxycarbonyl-NG-nitro-L-arginyl-L-proline Methyl Ester
Nα-Benzyloxycarbonyl-L-leucyl-NG-nitro-L-arginyl-L-proline
methylN2-(((benzyloxy)carbonyl)-L-leucyl)-Nw-nitroarginyl-L-prolinate
Nα-tert-butoxycarbonylseryltyrosine methyl ester
H-Tyr-OMe.HCl
Boc-L-Trp-ONp

DownStream

cyclo-L-Trp-L-His
(D-Ser4)-LHRH trifluoroacetate salt
(D-His2)-LHRH trifluoroacetate salt
LHRH (free acid) trifluoroacetate salt
(Des-Pyr1)-LHRH acetate salt
(2S)-2-[[(2S)-3-(1H-imidazol-5-yl)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]propanoyl]amino]-3-(1H-indol-3-yl)propanoic acid

Customs

[ HS Code ]: 2942000000

Articles

Neurokinin B: a new player in immune/inflammatory stress-mediated suppression of reproduction.

Endocrinology 155(7) , 2346-8, (2014)

Neurokinin B signaling in the female rat: a novel link between stress and reproduction.

Endocrinology 155(7) , 2589-601, (2014)

Acute systemic stress disrupts reproductive function by inhibiting pulsatile gonadotropin secretion. The underlying mechanism involves stress-induced suppression of the GnRH pulse generator, the funct...

TACR3 mutations disrupt NK3R function through distinct mechanisms in GnRH-deficient patients.

FASEB J. 28(4) , 1924-37, (2014)

Neurokinin B (NKB) and its G-protein-coupled receptor, NK3R, have been implicated in the neuroendocrine control of GnRH release; however, little is known about the structure-function relationship of t...

Gonadorelin
gonadorelin
Gonadorelin acetate
Gonadorelin Acetate
(D-Lys6)-Gonadorelin
(Des-Pyr1)-Gonadorelin
N-(3-chlorobenzyl)-2-(3-(dimethylamino)-4-(4-methoxyphenyl)-1H-pyrazol-1-yl)acetamide
2-(4-(4-chlorophenyl)-3-(dimethylamino)-1H-pyrazol-1-yl)-N-(3,4-dimethoxyphenyl)acetamide
2-(4-(4-chlorophenyl)-3-(dimethylamino)-1H-pyrazol-1-yl)-N-(3-methoxybenzyl)acetamide
N-(benzo[d][1,3]dioxol-5-yl)-2-(4-(4-chlorophenyl)-3-(dimethylamino)-1H-pyrazol-1-yl)acetamide
N-(benzo[d][1,3]dioxol-5-ylmethyl)-2-(4-(4-chlorophenyl)-3-(dimethylamino)-1H-pyrazol-1-yl)acetamide
2-(4-(4-chlorophenyl)-3-(dimethylamino)-1H-pyrazol-1-yl)-N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acetamide
N-(4-acetamidophenyl)-2-(4-(4-chlorophenyl)-3-(dimethylamino)-1H-pyrazol-1-yl)acetamide
N-cyclohexyl-2-(4-methyl-3,5-dioxo-3,4-dihydro-2H-pyridazino[4,5-b][1,4]thiazin-6(5H)-yl)acetamide
N-(2-chlorophenyl)-2-(4-methyl-3,5-dioxo-3,4-dihydro-2H-pyridazino[4,5-b][1,4]thiazin-6(5H)-yl)acetamide
2-{4-methyl-3,5-dioxo-2H,3H,4H,5H,6H-pyridazino[4,5-b][1,4]thiazin-6-yl}-N-[2-(trifluoromethyl)phenyl]acetamide

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