3,5-Pyridinedicarboxylic acid, 1,4-dihydro-4-(4-methoxyphenyl)-2,6-dimethyl-, diethyl ester (9CI)

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Names

[ CAS No. ]:
34014-60-3

[ Name ]:
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-4-(4-methoxyphenyl)-2,6-dimethyl-, diethyl ester (9CI)

[Synonym ]:
diethyl 2,6-dimethyl-4-p-methoxyphenyl-1,4-dihydropyridine-3,5-dicarboxylate
Ftorin
diethyl 1,4-dihydro-2,6-dimethyl-4-(4-methoxyphenyl)pyridine-3,5-dicarboxylate
1,4-Dihydro-2,6-dimethyl-4-(2-(trifluoromethyl)phenyl)-3,5-pyridinedicarboxylic acid diethyl ester
diethyl 2,6-dimethyl-4-(4-methoxyphenyl)-1,4-dihydropyridine-3,5-dicarboxylate
SK&Ftorin (pharmaceutical)
4-(2-Trifluoromethylphenyl)-3,5-dicarbethoxy-2,6-dimethyl-1,4-dihydropyridine
4-<2-(trifluoromethyl)phenyl>-3,5-dicarboethoxy-1,4-dihydrolutidine
diethyl 1,4-dihydro-2,6-dimethyl-4-[2-(trifluoromethyl)phenyl]3,5-pyridinedicarboxylate
3,5-dicarbethoxy-1,4-dihydro-2,6-dimethyl-4-(2-trifluoromethylphenyl)pyridine
2,6-Dimethyl-3,5-dicarbomethoxy-4-(o-trifluoromethylphenyl)-1,4-dihydropyridine [French]
diethyl 1,4-dihydro-4-(4-methoxyphenyl)-2,6-dimethylpyridine-3,5-dicarboxylate
diethyl 1,4-dihydro-2,6-dimethyl-4-(2-trifluoromethylphenyl)-pyridine-3,5-dicarboxylate
4-(4-methoxy-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester
3,5-diethoxycarbonyl-4-(4-methoxy)phenyl-2,6-dimethyl-1,4-dihydropyridine

Chemical & Physical Properties

[ Density]:
1.132g/cm3

[ Boiling Point ]:
481.7ºC at 760 mmHg

[ Molecular Formula ]:
C20H25NO5

[ Molecular Weight ]:
359.41600

[ Flash Point ]:
245.1ºC

[ Exact Mass ]:
359.17300

[ PSA ]:
73.86000

[ LogP ]:
3.38500

[ Index of Refraction ]:
1.525

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
US7979000
CHEMICAL NAME :
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-4-(p-methoxyphenyl)-2,6-dimethyl-, diethyl ester
CAS REGISTRY NUMBER :
34014-60-3
BEILSTEIN REFERENCE NO. :
0043785
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C20-H25-N-O5
MOLECULAR WEIGHT :
359.46
WISWESSER LINE NOTATION :
T6M DHJ B1 CVO2 DR DO1& EVO2 F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#01323

Safety Information

[ HS Code ]:
2933399090

Synthetic Route

Precursor & DownStream

Precursor

  • Ethyl acetoacetate
  • 4-Methoxybenzaldehyde
  • Ammonium acetate
  • Urea
  • Ethyl (2Z)-3-amino-2-butenoate
  • ethyl 3-aminocrotonate
  • N-[chloro(4-methoxyphenyl)methyl]pyridinium chloride

DownStream

  • 3,5-Pyridinedicarboxylicacid, 4-(4-methoxyphenyl)-2,6-dimethyl-, 3,5-diethyl ester

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%


Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 2-(7-Chloroimidazo[1,5-a]pyridin-1-yl)acetic acid
  • 4-Bromo-2-[2-(piperazin-1-yl)ethyl]phenol
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 5-Methoxy-2-(1H-1,2,3-triazol-1-yl)benzoic acid
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde