o,p'-dde

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Names

[ Name ]:
o,p'-dde

[Synonym ]:
2,4'-DDE
O,P'-DDE
1-chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethenyl]benzene
Benzene, 1-chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethenyl]-
EINECS 222-318-0
2-(2-Chlorophenyl)-2-(4-chlorophenyl)-1,1-dichloroethene
EINECS 200-659-6
1-Chloro-2-[2,2-dichloro-1-(4-chlorophényl)éthènyl]benzène
MFCD00036122
1-Chloro-2-[2,2-dichloro-1-(4-chlorophenyl)vinyl]benzene

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
380.6±37.0 °C at 760 mmHg

[ Melting Point ]:
78.32°C

[ Molecular Formula ]:
C₁₄H₈Cl₄

[ Molecular Weight ]:
318.025

[ Flash Point ]:
181.8±23.9 °C

[ Exact Mass ]:
315.938019

[ LogP ]:
6.22

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.622

[ Storage condition ]:
APPROX 4°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KV9454000

CHEMICAL NAME :: Ethylene, 1,1-dichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)-

CAS REGISTRY NUMBER :: 3424-82-6

BEILSTEIN REFERENCE NO. :: 1977640

LAST UPDATED :: 199712

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C14-H8-Cl4

MOLECULAR WEIGHT :: 318.02

WISWESSER LINE NOTATION :: GYGUYR DG&R BG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 880 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Cytogenetic analysis

TEST SYSTEM :: Rodent - rat Cells - not otherwise specified

DOSE/DURATION :: 10 ug/L

REFERENCE :: 34LXAP "Insecticide Biochemistry and Physiology," Wilkinson, C.F., ed., New York, Plenum Pub. Corp., 1976 Volume(issue)/page/year: -,555,1976

Safety Information

[ Symbol ]:

GHS02, GHS06, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H301 + H311 + H331-H370

[ Precautionary Statements ]:
P210-P260-P280-P301 + P310-P311

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US)

[ Hazard Codes ]:
F;T

[ Risk Phrases ]:
R22

[ Safety Phrases ]:
S7;S16;S24;S45

[ RIDADR ]:
UN 3077

[ RTECS ]:
KV9450000

[ Hazard Class ]:
9.0

[ HS Code ]:
2903999090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2903999090

[ Summary ]:
2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

Organochlorine pesticides and polychlorinated biphenyls in sediments and fish from freshwater cultured fish ponds in different agricultural contexts in north-eastern France.

Ecotoxicol. Environ. Saf. 77 , 35-44, (2012)

Organochlorine pesticides (HCB, HCH with α-, β-, and γ isomers, heptachlor, cis-heptachlor epoxyde, trans-heptachlor epoxyde, endosulfan with α- and β isomers, sulfate endosulfan, o,p'-DDT, p,p'-DDT, ...

DDT- and DDE-induced disruption of ovarian steroidogenesis in prepubertal porcine ovarian follicles: a possible interaction with the main steroidogenic enzymes and estrogen receptor beta.

J. Physiol. Pharmacol. 58(4) , 873-85, (2007)

We evaluated impact of DDT isomers, o, p'- DDT [1, 1-dichloro-2, 2-bis (p, p'-chlorophenyl) ethylene] and p, p'-DDT [1, 1, 1-trichloro-2, 2-bis (p-chlorophenyl) ethane], and their metabolites, o, p'-D...

Plasma concentrations of o,p'DDD, o,p'DDA, and o,p'DDE as predictors of tumor response to mitotane in adrenocortical carcinoma: results of a retrospective ENS@T multicenter study.

J. Clin. Endocrinol. Metab. 96(6) , 1844-51, (2011)

In patients with adrenocortical carcinoma (ACC) mitotane activity has been suggested to depend on plasma levels 14 mg/liter or greater and metabolite formation.The study was performed to confirm the c...

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