CHLOTAZOLE

Suppliers

Names

[ CAS No. ]:
35317-79-4

[ Name ]:
CHLOTAZOLE

[Synonym ]:
2,2,2-trichloro-1-thiazol-2-ylamino-ethanol
2,2,2-Trichlor-1-thiazol-2-ylamino-aethanol
Clotazol
Khlotazol
Chlotazole

Chemical & Physical Properties

[ Density]:
1.765g/cm3

[ Boiling Point ]:
301ºC at 760 mmHg

[ Molecular Formula ]:
C5H5Cl3N2OS

[ Molecular Weight ]:
247.53000

[ Flash Point ]:
135.8ºC

[ Exact Mass ]:
245.91900

[ PSA ]:
73.39000

[ LogP ]:
2.31660

[ Index of Refraction ]:
1.68

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KM4950000
CHEMICAL NAME :
Ethanol, 2,2,2-trichloro-1-(2-thiazolylamino)-
CAS REGISTRY NUMBER :
35317-79-4
BEILSTEIN REFERENCE NO. :
0152089
LAST UPDATED :
199612
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C5-H5-Cl3-N2-O-S
MOLECULAR WEIGHT :
247.53
WISWESSER LINE NOTATION :
T5N CSJ BMYQXGGG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 17,519,1983
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 46,213,1983
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
708 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FRXXBL French Demande Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #2400361
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - cat
DOSE/DURATION :
700 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 17,519,1983
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
700 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 17,519,1983

Synthetic Route

Precursor & DownStream

Precursor

  • 2-Aminothiazole
  • Chloral

DownStream


Related Compounds

  • 4-methyl-1-(1-methyl-1H-1,2,4-triazol-3-yl)cyclohex-2-en-1-ol
  • 1-(2,2-Dimethylpropyl)-4-methylcyclohex-2-en-1-ol
  • 4-Methyl-1-(4-methylfuran-2-yl)cyclohex-2-en-1-ol
  • 1-[(3,3-Dimethylcyclobutyl)methyl]-4-methylcyclohex-2-en-1-ol
  • 4-Methyl-1-[(5-methyl-1,3-thiazol-2-yl)methyl]cyclohex-2-en-1-ol
  • 4-ethyl-1-(1-methyl-1H-1,2,3-triazol-5-yl)cyclohex-2-en-1-ol
  • 4-ethyl-3-(4-methyl-4H-1,2,4-triazol-3-yl)cyclohexan-1-amine
  • 4-Ethyl-3-(2-methyl-1,3-thiazol-4-yl)cyclohexan-1-amine
  • 4-Ethyl-3-[(1,2,5-thiadiazol-3-yl)methyl]cyclohexan-1-amine
  • 4-Ethyl-3-[(1,2-thiazol-5-yl)methyl]cyclohexan-1-amine