Piribedil

Suppliers

Names

[ CAS No. ]:
3605-01-4

[ Name ]:
Piribedil

[Synonym ]:
2-[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]pyrimidine
Pyrimidine, 2-(4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl)-
2-(4-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)pyrimidine
Piribedilum [INN-Latin]
1-(2''-Pyrimidyl)-4-(methylene-3',4'-dioxybenzyl)piperazine
2-(4-Benzo[1,3]dioxol-5-ylmethyl-piperazin-1-yl)-pyrimidine
Piribedile [DCIT]
3-benzodioxol-5-ylmethyl)-1-piperazinyl]pyrimidine
2-[4-(1,3-Benzodioxol-5-ylmethyl)-1-piperazinyl]pyrimidine
Piribedil
ET 495
Trivastal
MFCD00868264
Trivastan
Pyrimidine, 2-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-
EU-4200
EINECS 222-764-6
2-[4-(3,4-Methylenedioxybenzyl)piperazino]pyrimidine

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
469.4±55.0 °C at 760 mmHg

[ Melting Point ]:
98 °C

[ Molecular Formula ]:
C16H18N4O2

[ Molecular Weight ]:
298.340

[ Flash Point ]:
237.7±31.5 °C

[ Exact Mass ]:
298.142975

[ PSA ]:
50.72000

[ LogP ]:
2.36

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.632

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UV9704000
CHEMICAL NAME :
Pyrimidine, 2-(4-piperonyl-1-piperazinyl)-
CAS REGISTRY NUMBER :
3605-01-4
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C16-H18-N4-O2
MOLECULAR WEIGHT :
298.38
WISWESSER LINE NOTATION :
T56 BO DO CHJ G1- AT6N DNTJ D- BT6N CNJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1460 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EJPHAZ European Journal of Pharmacology. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1967- Volume(issue)/page/year: 6,75,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
690 mg/kg
TOXIC EFFECTS :
Vascular - regional or general arteriolar or venous dilation Biochemical - Metabolism (Intermediary) - effect on inflammation or mediation of inflammation
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 11,1151,1968
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
88 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EJPHAZ European Journal of Pharmacology. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1967- Volume(issue)/page/year: 6,75,1969

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Piperonyl alcohol
  • 1-(2-PYRIMIDINYL) PIPERAZINE
  • piperonal
  • Formic Acid
  • tert-Butyl 4-(pyrimidin-2-yl)piperazine-1-carboxylate

DownStream

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • Piribedil D8
  • Piribedil N-Oxide
  • Piribedil mesylate
  • Piribedil Impurity 15
  • PIRIBEDIL HYDROCHLORIDE
  • Methyl pyrazine-2-carboxylate hydrochloride
  • (3-Chloro-6-methoxy-1-benzothiophen-2-yl)-phenylmethanone
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine