Piribedil

Suppliers

Names

[ Name ]:
Piribedil

[Synonym ]:
2-[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]pyrimidine
Pyrimidine, 2-(4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl)-
2-(4-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)pyrimidine
Piribedilum [INN-Latin]
1-(2''-Pyrimidyl)-4-(methylene-3',4'-dioxybenzyl)piperazine
2-(4-Benzo[1,3]dioxol-5-ylmethyl-piperazin-1-yl)-pyrimidine
Piribedile [DCIT]
3-benzodioxol-5-ylmethyl)-1-piperazinyl]pyrimidine
2-[4-(1,3-Benzodioxol-5-ylmethyl)-1-piperazinyl]pyrimidine
Piribedil
ET 495
Trivastal
MFCD00868264
Trivastan
Pyrimidine, 2-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-
EU-4200
EINECS 222-764-6
2-[4-(3,4-Methylenedioxybenzyl)piperazino]pyrimidine

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
469.4±55.0 °C at 760 mmHg

[ Melting Point ]:
98 °C

[ Molecular Formula ]:
C₁₆H₁₈N₄O₂

[ Molecular Weight ]:
298.340

[ Flash Point ]:
237.7±31.5 °C

[ Exact Mass ]:
298.142975

[ PSA ]:
50.72000

[ LogP ]:
2.36

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.632

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UV9704000

CHEMICAL NAME :: Pyrimidine, 2-(4-piperonyl-1-piperazinyl)-

CAS REGISTRY NUMBER :: 3605-01-4

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C16-H18-N4-O2

MOLECULAR WEIGHT :: 298.38

WISWESSER LINE NOTATION :: T56 BO DO CHJ G1- AT6N DNTJ D- BT6N CNJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1460 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EJPHAZ European Journal of Pharmacology. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1967- Volume(issue)/page/year: 6,75,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 690 mg/kg

TOXIC EFFECTS :: Vascular - regional or general arteriolar or venous dilation Biochemical - Metabolism (Intermediary) - effect on inflammation or mediation of inflammation

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 11,1151,1968

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 88 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EJPHAZ European Journal of Pharmacology. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1967- Volume(issue)/page/year: 6,75,1969

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%