2',3'-O-Isopropylideneguanosine

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Names

[ CAS No. ]:
362-76-5

[ Name ]:
2',3'-O-Isopropylideneguanosine

[Synonym ]:
2',3'-O-Isopropylidene-D-guanosine
9-[(3aR,4R,6R,6aR)-4-(hydroxymethyl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl]-2-azanyl-3H-purin-6-one
9-(2,3-O-Isopropylidene-β-D-ribofuranosyl)guanine
2-amino-9-((3aR,4R,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)-1H-purin-6(9H)-one
2',3'-O-Isopropylideneguanosine
2',3'-O-ISOPROPYLIDENE-GUANOSINE
9-[(3aR,4R,6R,6aR)-4-(hydroxymethyl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl]-2-amino-3H-purin-6-one
2',3'-O-(1-methylethylidene)-guanosine
2',3'-O-Isopropylide
EINECS 206-651-9
2-amino-9-[(3aR,4R,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl]-1,9-dihydro-6H-purin-6-one
2',3'-ISOPROPYLIDENE-GUANOSINE
2′,3′-O-Isopropylideneguanosine
Guanosine, 2',3'-O-(1-methylethylidene)-
9-[(3aR,4R,6R,6aR)-2,2-dimethyl-4-methylol-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl]-2-amino-3H-purin-6-one
2',3'-IPG
MFCD00057081

Chemical & Physical Properties

[ Density]:
1.9±0.1 g/cm3

[ Boiling Point ]:
647ºC at 760mmHg

[ Melting Point ]:
296 °C

[ Molecular Formula ]:
C13H17N5O5

[ Molecular Weight ]:
323.305

[ Flash Point ]:
345.1ºC

[ Exact Mass ]:
323.122955

[ PSA ]:
137.51000

[ LogP ]:
0.85

[ Index of Refraction ]:
1.828

[ Storage condition ]:
-20°C Freezer

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Precursor & DownStream

Precursor

  • Guanosine
  • Acetone
  • 2,2-Dimethoxypropane

DownStream

  • [2-(2-amino-6-oxo-3H-purin-9-yl)-7,7-dimethyl-3,6,8-trioxabicyclo[3.3.0]oct-4-yl]methylimino-imino-azanium
  • 6-O-Methyl Guanosine
  • Guanosine
  • 5'-Guanylic acid
  • GDP
  • N-(guanin-8-yl)-N-acetyl-2-aminofluorene
  • [2-(2-amino-6-oxo-3H-purin-9-yl)-7,7-dimethyl-3,6,8-trioxabicyclo[3.3.0]oct-4-yl]methyl acetate

Articles

Detection and identification of mutagens by the adducts formed upon reaction with guanosine derivatives.

IARC Sci. Publ. 70 , 413-418, (1986)

Mutagens present in crude samples such as heated glucose can be detected or identified by means of the adducts formed upon reaction with a fluorescent guanosine derivative (FG) or isopropylideneguanos...

Hydroxylation of guanine in nucleosides and DNA at the C-8 position by heated glucose and oxygen radical-forming agents.

Environ. Health Perspect. 67 , 111-116, (1986)

Heated glucose is mutagenic to Salmonella typhimurium TA 100 in the absence of S-9 mix. For identifying unknown mutagens in heated glucose (dry solid, 200 degrees C, 20 min), reaction with isopropylid...

Synthesis and application of a new 2',3'-isopropylidene guanosine substituted cap analog.

Bioorg. Med. Chem. Lett. 18 , 4828-4832, (2008)

The synthesis and biological evaluation of a new cap analog, which is modified at the C2' and C3' positions of N(7)-methylguanosine is reported. The new cap analog, P(1)-2',3'-isopropylidene, 7-methyl...


More Articles

Related Compounds

  • 5'-azido-2',3'-O-isopropylideneguanosine
  • 5'-azido-2',3'-O-isopropylideneguanosine
  • 5'-O-tosyl-2',3'-O-isopropylideneguanosine
  • 2-N-benzoyl-2',3'-O-isopropylideneguanosine
  • 8-allylamino-2',3'-O-isopropylideneguanosine
  • 2-N-propionyl-2',3'-O-isopropylideneguanosine
  • methyl 7-ethyl-1-oxo-3,4-dihydro-1H-2-benzopyran-3-carboxylate
  • methyl 6-bromo-1-oxo-3,4-dihydro-1H-2-benzopyran-3-carboxylate
  • 3-Fluoro-3-(methoxymethyl)piperidine
  • 2-(2,4,6-Trifluorophenyl)propanoic acid
  • [1-(3-Methyloxetan-3-yl)cyclobutyl]methanamine
  • 2-(3-Aminopyridin-2-yl)-2-methylpropanenitrile
  • (3-Cyclopentyloxetan-3-yl)methanol
  • 2-Ethyl-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine-7-carboxylic acid
  • 6-Bromo-3-iodo-2-methylpyrazolo[1,5-a]pyrimidine
  • 3-Cyano-5-methylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid
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