2',3'-O-Isopropylideneguanosine
2',3'-O-Isopropylideneguanosine structure
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Common Name | 2',3'-O-Isopropylideneguanosine | ||
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| CAS Number | 362-76-5 | Molecular Weight | 323.305 | |
| Density | 1.9±0.1 g/cm3 | Boiling Point | 647ºC at 760mmHg | |
| Molecular Formula | C13H17N5O5 | Melting Point | 296 °C | |
| MSDS | USA | Flash Point | 345.1ºC | |
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Detection and identification of mutagens by the adducts formed upon reaction with guanosine derivatives.
IARC Sci. Publ. 70 , 413-418, (1986) Mutagens present in crude samples such as heated glucose can be detected or identified by means of the adducts formed upon reaction with a fluorescent guanosine derivative (FG) or isopropylideneguanosine (IPG). After the reaction of IPG with heated glucose, t... |
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Hydroxylation of guanine in nucleosides and DNA at the C-8 position by heated glucose and oxygen radical-forming agents.
Environ. Health Perspect. 67 , 111-116, (1986) Heated glucose is mutagenic to Salmonella typhimurium TA 100 in the absence of S-9 mix. For identifying unknown mutagens in heated glucose (dry solid, 200 degrees C, 20 min), reaction with isopropylideneguanosine (IPG) was followed by isolation and characteri... |
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Synthesis and application of a new 2',3'-isopropylidene guanosine substituted cap analog.
Bioorg. Med. Chem. Lett. 18 , 4828-4832, (2008) The synthesis and biological evaluation of a new cap analog, which is modified at the C2' and C3' positions of N(7)-methylguanosine is reported. The new cap analog, P(1)-2',3'-isopropylidene, 7-methylguanosine-5'P(3)-guanosine-5'triphosphate was assayed with ... |
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"Single Addition" substrates for the synthesis of specific oligoribonucleotides with polynucleotide phosphorylase. Synthesis of 2'-(alpha-methoxyethy) nucleoside 5'-diphosphates.
Biochemistry 14 , 3152-3158, (1975) A number of synthetic methods for the preparation of the 2-O-(alpha-methoxyethyl) derivatives of the 5-diphosphates of adenosine, cytidine, guanosine, and uridine have been studied in order to provide nucleotide substrates that can be applied to the synthesis... |