Carnosic acid

Suppliers

Names

[ Name ]:
Carnosic acid

[Synonym ]:
Salvin
4a(2H)-Phenanthrenecarboxylic acid, 1,3,4,9,10,10a-hexahydro-5,6-dihydroxy-1,1-dimethyl-7-(1-methylethyl)-, (4aR,10aS)-
Carnosic acid
RoseOx
11,12-Dihydroxyabieta-8,11,13-trien-20-oic acid
Carnosic acid
(4aR,10aS)-5,6-dihydroxy-1,1-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene-4a-carboxylic acid
MFCD02259459
Carsonic acid
Carnosolic Acid

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
506.4±50.0 °C at 760 mmHg

[ Melting Point ]:
190 °C

[ Molecular Formula ]:
C₂₀H₂₈O₄

[ Molecular Weight ]:
332.434

[ Flash Point ]:
274.2±26.6 °C

[ Exact Mass ]:
332.198761

[ PSA ]:
77.76000

[ LogP ]:
4.93

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.576

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Redox-dependent induction of antioxidant defenses by phenolic diterpenes confers stress tolerance in normal human skin fibroblasts: Insights on replicative senescence.

Free Radic. Biol. Med. 83 , 262-72, (2015)

Mild stress-induced hormesis represents a promising strategy for targeting the age-related accumulation of molecular damage and, therefore, for preventing diseases and achieving healthy aging. Fruits,...

Carnosol Is a Potent Lung Protective Agent: Experimental Study on Mice.

Transplant. Proc. 47 , 1657-61, (2015)

Oxidative stress has been implicated in various disease states and ischemia/reperfusion injury is a direct consequence of oxidative stress in lung transplantation. Because the success rate of organ tr...

Enhanced Eryptosis Following Exposure to Carnosic Acid.

Cell Physiol. Biochem. 37 , 1779-91, (2015)

The phenolic abietane diterpene component of rosemary and sage, carnosic acid, may either induce or inhibit apoptosis of nucleated cells. The mechanisms involved in the effects of carnosic acid includ...