MST312

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Names

[ CAS No. ]:
368449-04-1

[ Name ]:
MST312

[Synonym ]:
telomerase inhibitor IX
IN1063
N,N'-1,3-Phenylenebis-[2,3-dihydroxy-benzamide]
N,N'-bis(2,3-dihydroxybenzoyl)-1,3-phenylenediamine
N,N-1,3-phenylenebis-(2,3-dihydroxybenzamide)
MST-312
1,3-bis(2,3-dihydroxybenzamido)benzene
Benzamide,N,N'-1,3-phenylenebis[2,3-dihydroxy
MST312

Chemical & Physical Properties

[ Molecular Formula ]:
C20H16N2O6

[ Molecular Weight ]:
380.35100

[ Exact Mass ]:
380.10100

[ PSA ]:
146.10000

[ LogP ]:
3.78160

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H400

[ Precautionary Statements ]:
P273

[ RIDADR ]:
UN 3077 9 / PGIII

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • m-Phenylenediamine
  • 2,3-DIMETHOXYBENZOYLCHLORIDE

DownStream

Articles

MST-312 Alters Telomere Dynamics, Gene Expression Profiles and Growth in Human Breast Cancer Cells.

J. Nutrigenet. Nutrigenomics 7 , 283-98, (2015)

Targeting telomerase is a potential cancer management strategy given that it allows unlimited cellular replication in the majority of cancers. Dysfunctional telomeres are recognized as double-strand b...

Fluorescence-based duplex-quadruplex competition test to screen for telomerase RNA quadruplex ligands.

Nucleic Acids Res. 39 , e21, (2011)

RNA and DNA guanine-rich sequences can adopt unusual structures called Guanine quadruplexes (G4). A quadruplex-prone RNA sequence is present at the 5'-end of the 451-nt-long RNA component of telomeras...


More Articles

Related Compounds

  • [4-[2-[4-(2-methylpropoxycarbonyloxymethyl)-3,5-dioxopiperazin-1-yl]ethyl]-2,6-dioxopiperazin-1-yl]methyl 2-methylpropyl carbonate
  • S-312-d
  • BAF-312 fumarate
  • simotaxel
  • Cardioprotectant
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  • 2-Benzyl 8-methyl 5-hydroxy-1,2,3,4-tetrahydro-2,6-naphthyridine-2,8-dicarboxylate
  • benzyl N-[4-(3,4-dihydroxyphenyl)-1,3-thiazol-2-yl]carbamate
  • 1,3-dimethyl-2,4-dioxo-5-(2,2,2-trifluoroacetamido)-1H,2H,3H,4H-thieno[2,3-d]pyrimidine-6-carboxylic acid
  • (2R)-2-(2,2,2-trifluoroacetamido)-3-(3,4,5-trimethoxyphenyl)propanoic acid
  • 2-(4-Hydroxy-3-methoxyphenyl)-3-(2,2,2-trifluoroacetyl)-1,3-thiazolidine-4-carboxylic acid
  • (2S)-3-(4-hydroxy-3-methoxyphenyl)-2-(2,2,2-trifluoroacetamido)propanoic acid
  • 2-(3,4-Dimethoxyphenyl)-2-(2,2,2-trifluoroacetamido)acetic acid
  • 3-(3-Hydroxypropoxy)-4-(2,2,2-trifluoroacetamido)benzoic acid
  • 3-(4-Hydroxy-3-methoxyphenyl)-2-(2,2,2-trifluoroacetamido)propanoic acid
  • (2S)-3-(3,4-dihydroxyphenyl)-2-methyl-2-(2,2,2-trifluoroacetamido)propanoic acid