MST312

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Names

[ Name ]:
MST312

[Synonym ]:
telomerase inhibitor IX
IN1063
N,N'-1,3-Phenylenebis-[2,3-dihydroxy-benzamide]
N,N'-bis(2,3-dihydroxybenzoyl)-1,3-phenylenediamine
N,N-1,3-phenylenebis-(2,3-dihydroxybenzamide)
MST-312
1,3-bis(2,3-dihydroxybenzamido)benzene
Benzamide,N,N'-1,3-phenylenebis[2,3-dihydroxy
MST312

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₀H₁₆N₂O₆

[ Molecular Weight ]:
380.35100

[ Exact Mass ]:
380.10100

[ PSA ]:
146.10000

[ LogP ]:
3.78160

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H400

[ Precautionary Statements ]:
P273

[ RIDADR ]:
UN 3077 9 / PGIII

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

m-Phenylenediamine
2,3-DIMETHOXYBENZOYLCHLORIDE

DownStream

Articles

MST-312 Alters Telomere Dynamics, Gene Expression Profiles and Growth in Human Breast Cancer Cells.

J. Nutrigenet. Nutrigenomics 7 , 283-98, (2015)

Targeting telomerase is a potential cancer management strategy given that it allows unlimited cellular replication in the majority of cancers. Dysfunctional telomeres are recognized as double-strand b...

Fluorescence-based duplex-quadruplex competition test to screen for telomerase RNA quadruplex ligands.

Nucleic Acids Res. 39 , e21, (2011)

RNA and DNA guanine-rich sequences can adopt unusual structures called Guanine quadruplexes (G4). A quadruplex-prone RNA sequence is present at the 5'-end of the 451-nt-long RNA component of telomeras...

[4-[2-[4-(2-methylpropoxycarbonyloxymethyl)-3,5-dioxopiperazin-1-yl]ethyl]-2,6-dioxopiperazin-1-yl]methyl 2-methylpropyl carbonate
S-312-d
BAF-312 fumarate
simotaxel
Cardioprotectant
Siponimod
2-methyl-3-(2-phenylethyl)pyrimido[1,2-a]benzimidazol-4(1H)-one
7-ethyl-8-(4-fluorophenyl)-4-methyl-N-(2-methylphenyl)pyrazolo[5,1-c][1,2,4]triazine-3-carboxamide
2-[(1-Ethylindol-3-yl)methylene]-3-oxobenzo[3,4-b]furan-6-yl 3-methoxybenzoate
2-Hydroxy-4-nitrobenzenediazonium ion
3-methyl-1-(4-methylphenyl)-4-(2-phenylethyl)-1H-pyrazol-5-ol
2-[(5-Bromo-2-methoxyphenyl)methylene]-6-hydroxy-7-{[methylbenzylamino]methyl} benzo[b]furan-3-one
(2Z)-2-(5-bromo-2-methoxybenzylidene)-7-[(dibutylamino)methyl]-6-hydroxy-1-benzofuran-3(2H)-one
(2Z)-2-(biphenyl-4-ylmethylidene)-6-hydroxy-7-[(2-methylpiperidin-1-yl)methyl]-1-benzofuran-3(2H)-one
Ethyl 3,4-dihydro-2H-chromene-4-carboxylate
3-Quinuclidinyl thiochromane-4-carboxylate

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