oxalic bis(cyclohexylidenehydrazide)

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Names

[ CAS No. ]:
370-81-0

[ Name ]:
oxalic bis(cyclohexylidenehydrazide)

[Synonym ]:
Dicyclohexanoneoxaly dihydrazone
MFCD00001659
Bis(cyclohexanone) Oxalyldihydrazone
oxalic bis(cyclohexylidenehydrazide)
N,N'-bis(cyclohexylideneamino)oxamide
Oxalic acid bis(cyclohexylidenehydrazide)
Ethanedioic acid, bis(2-cyclohexylidenehydrazide)
Cuprizon,Cuprizone,Oxalic acid bis(cyclohexylidenehydrazide)
N',N'-Dicyclohexylideneethanedihydrazide
Bis(cyclohexanone)oxalyldihydrazone
Cupferazone
Oxalic Acid Bis-(Cyclohexylidenehydrazide)
EINECS 206-729-2

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Melting Point ]:
210-214 °C(lit.)

[ Molecular Formula ]:
C14H22N4O2

[ Molecular Weight ]:
278.350

[ Exact Mass ]:
278.174286

[ PSA ]:
82.92000

[ LogP ]:
0.85

[ Index of Refraction ]:
1.626

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RO2520000
CHEMICAL NAME :
Oxalic acid, bis(cyclohexylidenehydrazide)
CAS REGISTRY NUMBER :
370-81-0
BEILSTEIN REFERENCE NO. :
2388004
LAST UPDATED :
199701
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C14-H22-N4-O2
MOLECULAR WEIGHT :
278.40
WISWESSER LINE NOTATION :
L6YTJ AUNMVVMNU- AL6YTJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
29400 mg/kg/7W-C
TOXIC EFFECTS :
Brain and Coverings - other degenerative changes Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
20160 mg/kg/8W-C
TOXIC EFFECTS :
Brain and Coverings - other degenerative changes Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - monoamine oxidase
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
24 gm/kg
SEX/DURATION :
female 3-22 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Newborn - live birth index (measured after birth)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
40 gm/kg
SEX/DURATION :
female 3-22 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Newborn - stillbirth

MUTATION DATA

TEST SYSTEM :
Rodent - rat
DOSE/DURATION :
14 gm/kg/14D (Continuous)
REFERENCE :
EJBCAI European Journal of Biochemistry. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1967- Volume(issue)/page/year: 47,313,1974

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R21/22

[ Safety Phrases ]:
S24/25-S2

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
RO2520000

[ Packaging Group ]:
I; II; III

[ Hazard Class ]:
6.1

[ HS Code ]:
29280090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Ethanedihydrazide
  • Cyclohexanone

DownStream

Customs

[ HS Code ]: 2928000090

[ Summary ]:
2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

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