4-Carboxy-2,2,6,6-tetramethylpiperidine-N-oxyl

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Names

[ Name ]:
4-Carboxy-2,2,6,6-tetramethylpiperidine-N-oxyl

[Synonym ]:
4-Carboxy-TEMPO
MFCD00134569
4-Carboxy-TEMPO,free radical
Tempo carboxylate
4-COOH-TEMPO
1-oxyl-2,2,6,6-tetramethylpiperidin-4-carboxylic acid radical
4-Carboxy-2,2,6,6-tetramethylpiperidine 1-oxyl
4-Carboxy-2,2,6,6-tetramethylpiperidine-N-oxyl
Tca meglumine
Tempo carboxylic acid
4-Carboxy-TEMPO Free Radical
carboxy-TEMPO
(4-Carboxy-2,2,6,6-tetramethylpiperidin-1-yl)oxidanyl
(4-Carboxy-2,2,6,6-tetramethyl-1-piperidinyl)oxidanyl
1-Piperidinyloxy, 4-carboxy-2,2,6,6-tetramethyl-
4-Carboxy-2,2,6,6-tetramethylpiperidine 1-Oxyl Free Radical
4-Carboxy-2,2,6,6-tetramethylpiperidinyloxy,free radical

Chemical & Physical Properties

[ Melting Point ]:
185-189ºC(lit.)

[ Molecular Formula ]:
C₁₀H₁₈NO₃

[ Molecular Weight ]:
200.255

[ Exact Mass ]:
200.128662

[ PSA ]:
40.54000

[ LogP ]:
1.62360

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Articles

Molecular diffusion into ferritin: pathways, temperature dependence, incubation time, and concentration effects.

Biophys. J. 78(4) , 2049-59, (2000)

The detailed kinetics of permeation and effusion of small nitroxide spin probe radicals with the protein shells of horse spleen ferritin (HoSF) and human H-chain ferritin (HuHF) and a 3-fold channel v...

Molecular diffusion into horse spleen ferritin: a nitroxide radical spin probe study.

Biophys. J. 71 , 1587, (1996)

Electron paramagnetic resonance spectroscopy and gel permeation chromatography were employed to study the molecular diffusion of a number of small nitroxide spin probes (approximately 7-9 A diameter) ...

Oligonucleotide and Parylene Surface Coating of Polystyrene and ePTFE for Improved Endothelial Cell Attachment and Hemocompatibility.

Int J Biomater 2012 , 397813, (2012)

In vivo self-endothelialization by endothelial cell adhesion on cardiovascular implants is highly desirable. DNA-oligonucleotides are an intriguing coating material with nonimmunogenic characteristics...

4-amino-4-carboxy-2,2,6,6-tetramethylpiperidine-N-oxyl
4-<(9-fluorenylmethyloxycarbonyl)amino>-4-carboxy-2,2,6,6-tetramethylpiperidine-N-oxyl
4-crotonoyloxy-2,2,6,6-tetramethylpiperidine-N-oxyl
4-butylamino-2,2,6,6-tetramethylpiperidine-N-oxyl
5-amino-(2,2,6,6-tetramethylpiperidine-N-oxyl)uridine 5'-triphosphate
N-Boc-2,2,6,6-tetramethylpiperidine-N-oxyl-4-amino-4-carboxylic Acid
(2-ethoxyphenyl)(4-(1-(2-fluorophenyl)-1H-imidazol-2-yl)piperazin-1-yl)methanone hydrochloride
(3,4-dimethoxyphenyl)(4-(1-(2-fluorophenyl)-1H-imidazol-2-yl)piperazin-1-yl)methanone hydrochloride
(2,4-dichlorophenyl)(4-(1-(2-fluorophenyl)-1H-imidazol-2-yl)piperazin-1-yl)methanone hydrochloride
(2-chloro-6-fluorophenyl)(4-(1-(2-fluorophenyl)-1H-imidazol-2-yl)piperazin-1-yl)methanone hydrochloride
2-(4-ethoxyphenoxy)-1-(4-(1-(2-fluorophenyl)-1H-imidazol-2-yl)piperazin-1-yl)ethanone hydrochloride
(4-(1-(3-chlorophenyl)-1H-imidazol-2-yl)piperazin-1-yl)(phenyl)methanone hydrochloride
(4-(1-(3-chlorophenyl)-1H-imidazol-2-yl)piperazin-1-yl)(3,5-dimethoxyphenyl)methanone hydrochloride
1-(4-(1-(3-chlorophenyl)-1H-imidazol-2-yl)piperazin-1-yl)-2-(3-methoxyphenoxy)ethanone hydrochloride
N-(2-Ethoxyphenyl)acridin-9(10H)-imine--hydrogen chloride (1/1)
1-(4-(1-(3-chlorophenyl)-1H-imidazol-2-yl)piperazin-1-yl)-4-phenylbutan-1-one hydrochloride

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