4-Carboxy-2,2,6,6-tetramethylpiperidine-N-oxyl
4-Carboxy-2,2,6,6-tetramethylpiperidine-N-oxyl structure
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Common Name | 4-Carboxy-2,2,6,6-tetramethylpiperidine-N-oxyl | ||
|---|---|---|---|---|
| CAS Number | 37149-18-1 | Molecular Weight | 200.255 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C10H18NO3 | Melting Point | 185-189ºC(lit.) | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Molecular diffusion into ferritin: pathways, temperature dependence, incubation time, and concentration effects.
Biophys. J. 78(4) , 2049-59, (2000) The detailed kinetics of permeation and effusion of small nitroxide spin probe radicals with the protein shells of horse spleen ferritin (HoSF) and human H-chain ferritin (HuHF) and a 3-fold channel variant D131H+E134H of HuHF were studied by electron paramag... |
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Molecular diffusion into horse spleen ferritin: a nitroxide radical spin probe study.
Biophys. J. 71 , 1587, (1996) Electron paramagnetic resonance spectroscopy and gel permeation chromatography were employed to study the molecular diffusion of a number of small nitroxide spin probes (approximately 7-9 A diameter) into the central cavity of the iron-storage protein ferriti... |
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Oligonucleotide and Parylene Surface Coating of Polystyrene and ePTFE for Improved Endothelial Cell Attachment and Hemocompatibility.
Int J Biomater 2012 , 397813, (2012) In vivo self-endothelialization by endothelial cell adhesion on cardiovascular implants is highly desirable. DNA-oligonucleotides are an intriguing coating material with nonimmunogenic characteristics and the feasibility of easy and rapid chemical fabrication... |
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Paramagnetic NMR investigation of dendrimer-based host-guest interactions.
PLoS ONE 8 , e64722, (2013) In this study, the host-guest behavior of poly(amidoamine) (PAMAM) dendrimers bearing amine, hydroxyl, or carboxylate surface functionalities were investigated by paramagnetic NMR studies. 2,2,6,6-Tetramethylpiperidinyloxy (TEMPO) derivatives were used as par... |
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The impact of carboxy nitroxide antioxidants on irradiated ataxia telangiectasia cells.
Free Radic. Biol. Med. 37(7) , 946-52, (2004) Three water-soluble carboxy nitroxide antioxidants, 5-carboxy-1,1,3,3-tetramethylisoindolin-2-yloxyl, 4-carboxy-2,2,6,6-tetramethylpiperidin-1-yloxyl, and 3-carboxy-2,2,5,5-tetramethylpyrrolidin-1-yloxyl, show significant impact on the postirradiation surviva... |
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Intrathecal administration of nitroxides as potential contrast agents for MR imaging.
Radiology 163(1) , 239-43, (1987) The diagnosis of various disorders of the cerebrospinal fluid (CSF) with magnetic resonance (MR) imaging may require the intrathecal administration of a paramagnetic contrast agent. Furthermore, the CSF route provides direct access to the brain, circumventing... |
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Ideal imaging in MR: contrast-enhancing pharmaceuticals. Evaluation of tempo carboxylic acid as nitroxide diagnostic agent.
Eur. J. Radiol. 6(1) , 48-52, (1986) The meglumine salt of TCA, a piperidinyl nitroxide stable free radical derivative, was tested as an NMR contrast enhancer. This report of its use in animals indicates its usefulness in the enhancement of signal intensity of the kidney and bladder. |
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Pharmacokinetic study of tempo carboxylic acid, a nitroxyl MRI contrast media, in control and streptozocin diabetic rats.
J. Pharm. Pharmacol. 41(8) , 561-3, (1989) The pharmacokinetics of tempo carboxylic acid (TCA), a nitroxyl contrast medium have been evaluated in control and streptozocin-diabetic rats. Previous magnetic resonance imaging (MRI) studies in diabetic rats showed prolongation of contrast visualization in ... |
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Nitroxide-mediated oxidation of cellulose using TEMPO derivatives: HPSEC and NMR analyses of the oxidized products. Shibata I and Isogai A.
Cellulose 10(4) , 335-341, (2003)
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Comparison of two MCM-41 grafted TEMPO catalysts in selective alcohol oxidation. Brunel D, et al.
Appl. Catal. A Gen. 213(1) , 73-82, (2001)
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