3,5-Difluoroaniline

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Names

[ CAS No. ]:
372-39-4

[ Name ]:
3,5-Difluoroaniline

[Synonym ]:
3,5-Difluoroaniline
ZR CF EF
3,5-DIFLUOROBENZENEAMINE
3,5-Difluorophenylamine
3,5-difluoro-aniline
3,5-Difluorobenzenamine
3,4-difluoro-phenylamine
Benzenamine,3,5-difluoro
5-Difluoroaniline
3,5-Difluoronitroaniline
3,5-Difluor-anilin
EINECS 206-752-8
Benzenamine, 3,5-difluoro-
MFCD00007763

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
185.4±20.0 °C at 760 mmHg

[ Melting Point ]:
37-41 °C(lit.)

[ Molecular Formula ]:
C6H5F2N

[ Molecular Weight ]:
129.107

[ Flash Point ]:
75.0±0.0 °C

[ Exact Mass ]:
129.039001

[ PSA ]:
26.02000

[ LogP ]:
1.87

[ Vapour Pressure ]:
0.7±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.521

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302 + H312 + H332

[ Precautionary Statements ]:
P280

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R20/21/22;R36/37/38

[ Safety Phrases ]:
S28-S36/37/39-S26

[ RIDADR ]:
UN 1325 4.1/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
2921420090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-methoxyethanol
  • Hydrazine hydrate
  • Methyl tert-butyl ether
  • 1,3,5-Trifluorobenzene
  • 3,5-Difluoronitrobenzene
  • 2,4-Difluoro-6-nitroaniline
  • 2',4'-Difluoroacetanilide
  • Sulfuric acid

DownStream

  • Benzene,1,3,5-trichloro-2,4,6-trifluoro-
  • 1,3,5-Trifluoro-2-nitrobenzene
  • 3,5-Difluorobenzoic acid
  • 2,6-Difluoroaniline
  • Ethyl 4-chloro-5,7-difluoroquinoline-3-carboxylate
  • 1,3,5-Trifluorobenzene
  • 1-Chloro-3,5-difluorobenzene
  • 1-Bromo-3,5-difluorobenzene
  • N-(3,5-DIFLUORO-PHENYL)-FORMAMIDE
  • N-(3,5-difluorophenyl)-2,3,4,5,6-pentafluoroaniline

Customs

[ HS Code ]: 2921420090

[ Summary ]:
HS:2921420090 aniline derivatives and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Haloaniline-induced in vitro nephrotoxicity: effects of 4-haloanilines and 3,5-dihaloanilines.

Toxicol. Lett. 114(1) , 125-33, (2000)

Haloanilines are widely used as chemical intermediates in the manufacture of pesticides, dyes and drugs. The purpose of this study was to examine the in vitro nephrotoxic effects of the four 4-haloani...

Further studies on the carcinogenicity of dyes related to 4-dimethylaminoazobenzene; the requirement for an unsubstituted 2-position.

Cancer Res. 17(5) , 387-98, (1957)


More Articles

Related Compounds

  • 2-nitro-3,5-difluoroaniline
  • 4-Bromo-3,5-difluoroaniline
  • 4-nitro-3,5-difluoroaniline
  • 4-Bromo-3,5-difluoroaniline
  • 4-nitro-3,5-difluoroaniline
  • N-ethyl-3,5-difluoroaniline
  • N,4-dimethyl-3-(1-methyl-1H-pyrazol-4-yl)cyclohexan-1-amine
  • 5-(4-Aminobut-1-en-2-yl)-2-nitrophenol
  • (N-(5H-Cyclopenta(2,1-b:3,4-b')dipyridin-5-ylidene-kappaN1,kappaN9)benzenediamine)bis(1,10-phenanthroline-kappaN1,kappaN10)ruthenium-(2+)-(OC-6-22) diperchlorate
  • Magainin IIa
  • 2-[2-(Propan-2-yl)-1,3-thiazol-5-yl]ethanimidamide
  • Bis(2,2'-bipyridine-kappaN1,kappaN1')(N-(5H-cyclopenta(2,1-b:3,4-b')dipyridin-5-ylidene-kappaN1,kappaN9)-1,4-benzenediamine)-ruthenium-(2+)-(OC-6-22) diperchlorate
  • 1-[(1-Bromo-2-methylpropan-2-yl)oxy]-5-methylhexane
  • 5'-(2-(10-(2-Hydroxyethyl)phenazinium-2-yl)aminoethylaminophosphinyl)-3'-(4-(2-chloroethyl)methylaminophenyl)methylene-oligonucleotide
  • Aluminum, bis(benzoato-kappaO)(2-ethylhexanoato-kappaO)tri-mu-oxotri-, cyclo
  • Bis(2,2'-bipyridine-kappaN1,kappaN1')(N-(5H-cyclopenta(2,1-b:3,4-b')dipyridin-5-ylidene-kappaN1,kappaN9)benzenamine)ruthenium(2+) diperchlorate
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