3,5-Difluoroaniline
3,5-Difluoroaniline structure
|
Common Name | 3,5-Difluoroaniline | ||
|---|---|---|---|---|
| CAS Number | 372-39-4 | Molecular Weight | 129.107 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 185.4±20.0 °C at 760 mmHg | |
| Molecular Formula | C6H5F2N | Melting Point | 37-41 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 75.0±0.0 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 3,5-Difluoroaniline |
|---|---|
| Synonym | More Synonyms |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 185.4±20.0 °C at 760 mmHg |
| Melting Point | 37-41 °C(lit.) |
| Molecular Formula | C6H5F2N |
| Molecular Weight | 129.107 |
| Flash Point | 75.0±0.0 °C |
| Exact Mass | 129.039001 |
| PSA | 26.02000 |
| LogP | 1.87 |
| Vapour Pressure | 0.7±0.4 mmHg at 25°C |
| Index of Refraction | 1.521 |
| InChIKey | KQOIBXZRCYFZSO-UHFFFAOYSA-N |
| SMILES | Nc1cc(F)cc(F)c1 |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302 + H312 + H332 |
| Precautionary Statements | P280 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn:Harmful |
| Risk Phrases | R20/21/22;R36/37/38 |
| Safety Phrases | S28-S36/37/39-S26 |
| RIDADR | UN 1325 4.1/PG 2 |
| WGK Germany | 3 |
| Packaging Group | III |
| Hazard Class | 6.1 |
| HS Code | 2921420090 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
|
~90%
3,5-Difluoroaniline CAS#:372-39-4 |
| Literature: Ishihara Sangyo Kaisha Ltd. Patent: US5399767 A1, 1995 ; |
|
~71%
3,5-Difluoroaniline CAS#:372-39-4 |
| Literature: Safina, Larisa Yu.; Selivanova, Galina A.; Koltunov, Konstantin Yu.; Shteingarts, Vitalij D. Tetrahedron Letters, 2009 , vol. 50, # 37 p. 5245 - 5247 |
|
~%
3,5-Difluoroaniline CAS#:372-39-4 |
| Literature: BASF Corporation Patent: US6127577 A1, 2000 ; |
|
~%
3,5-Difluoroaniline CAS#:372-39-4 |
| Literature: Shtark, A. A.; Chuikova, T. V.; Selivanova, G. A.; Shteingarts, V. D. Journal of Organic Chemistry USSR (English Translation), 1987 , vol. 23, p. 2271 - 2276 Zhurnal Organicheskoi Khimii, 1987 , vol. 23, # 12 p. 2574 - 2580 |
|
~%
3,5-Difluoroaniline CAS#:372-39-4 |
| Literature: Finger et al. Journal of the American Chemical Society, 1951 , vol. 73, p. 153 Journal of the American Chemical Society, 1959 , vol. 81, p. 94,98 |
|
~%
3,5-Difluoroaniline CAS#:372-39-4 |
| Literature: Finger et al. Journal of the American Chemical Society, 1951 , vol. 73, p. 153 Journal of the American Chemical Society, 1959 , vol. 81, p. 94,98 |
|
~%
3,5-Difluoroaniline CAS#:372-39-4 |
| Literature: Finger et al. Journal of the American Chemical Society, 1951 , vol. 73, p. 153 Journal of the American Chemical Society, 1959 , vol. 81, p. 94,98 |
|
~%
3,5-Difluoroaniline CAS#:372-39-4
Learn More
|
| Literature: Carlin; Heininger Journal of the American Chemical Society, 1955 , vol. 77, p. 2272,2277 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 8 | |
|---|---|
| DownStream 10 | |
CAS#:319-88-0
CAS#:315-14-0
CAS#:455-40-3
CAS#:5509-65-9
CAS#:311346-69-7
CAS#:1435-43-4
CAS#:461-96-1
CAS#:198077-69-9
CAS#:1111790-44-3This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2921420090 |
|---|---|
| Summary | HS:2921420090 aniline derivatives and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
|
Haloaniline-induced in vitro nephrotoxicity: effects of 4-haloanilines and 3,5-dihaloanilines.
Toxicol. Lett. 114(1) , 125-33, (2000) Haloanilines are widely used as chemical intermediates in the manufacture of pesticides, dyes and drugs. The purpose of this study was to examine the in vitro nephrotoxic effects of the four 4-haloani... |
|
|
Further studies on the carcinogenicity of dyes related to 4-dimethylaminoazobenzene; the requirement for an unsubstituted 2-position.
Cancer Res. 17(5) , 387-98, (1957)
|
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 3,5-Difluoroaniline |
| ZR CF EF |
| 3,5-DIFLUOROBENZENEAMINE |
| 3,5-Difluorophenylamine |
| 3,5-difluoro-aniline |
| 3,5-Difluorobenzenamine |
| 3,4-difluoro-phenylamine |
| Benzenamine,3,5-difluoro |
| 5-Difluoroaniline |
| 3,5-Difluoronitroaniline |
| 3,5-Difluor-anilin |
| EINECS 206-752-8 |
| MFCD00007763 |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the molecular formula of 3,5-Difluoroaniline? |
| A: Molecular formula of 3,5-Difluoroaniline is C6H5F2N. |
| Q: What is the melting point of 3,5-Difluoroaniline? |
| A: Melting point of 3,5-Difluoroaniline is 37-41 °C(lit.). |
| Q: What is the CAS number of 3,5-Difluoroaniline? |
| A: CAS number of 3,5-Difluoroaniline is 372-39-4. |
| Q: What is the LogP of 3,5-Difluoroaniline? |
| A: LogP of 3,5-Difluoroaniline is 1.87. |
| Q: What is the English name of 3,5-Difluoroaniline? |
| A: The English name of 3,5-Difluoroaniline is 3,5-Difluoroaniline. |
| Q: What is the molecular weight of 3,5-Difluoroaniline? |
| A: Molecular weight of 3,5-Difluoroaniline is 129.107. |
| Q: What is the boiling point of 3,5-Difluoroaniline? |
| A: Boiling point of 3,5-Difluoroaniline is 185.4±20.0 °C at 760 mmHg. |
| Q: What is the safety information for 3,5-Difluoroaniline? |
| A: Safety information for 3,5-Difluoroaniline: S28-S36/37/39-S26. |
| Q: What is the InChIKey of 3,5-Difluoroaniline? |
| A: InChIKey of 3,5-Difluoroaniline is KQOIBXZRCYFZSO-UHFFFAOYSA-N. |
| Q: What are the upstream materials of 3,5-Difluoroaniline? |
| A: Related upstream materials(CAS) of 3,5-Difluoroaniline: 109-86-4;7803-57-8;1634-04-4;372-38-3;2265-94-3;364-30-7;399-36-0;7664-93-9. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |
| Henan Tianfu Chemical Co., Ltd. |