3'-Amino-2'-hydroxy-3-biphenylcarboxylic acid

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Names

[ CAS No. ]:
376592-93-7

[ Name ]:
3'-Amino-2'-hydroxy-3-biphenylcarboxylic acid

[Synonym ]:
bip030
3'-Amino-2'-hydroxy-3-biphenylcarboxylic acid
[1,1'-Biphenyl]-3-carboxylic acid, 3'-amino-2'-hydroxy-
3'-amino-2'-hydroxy-biphenyl-3-carboxylic acid
3'-amino-2'-hydroxybiphenyl-3-carboxylic acid
Eltrombopag olamine Intermediate 1

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
474.8±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C13H11NO3

[ Molecular Weight ]:
229.231

[ Flash Point ]:
241.0±28.7 °C

[ Exact Mass ]:
229.073898

[ PSA ]:
83.55000

[ LogP ]:
1.48

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.686

Safety Information

[ HS Code ]:
2922509090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 5'-chloro-2'-hydroxy-3'-nitro-[1,1'-Biphenyl]-3-carboxylic acid
  • 2'-Hydroxy-3'-nitro-[1,1'-biphenyl]-3-carboxylic acid
  • 2-Bromo-4-chlorophenol
  • 3-Carboxyphenylboronic acid
  • 5'-Chloro-2'-hydroxy-3-biphenylcarboxylic acid
  • 2-nitro-4-chlorophenol
  • 2-Bromo-4-chloro-6-nitrophenol

DownStream

Customs

[ HS Code ]: 2922509090

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Related Compounds

  • 3'-Amino-2'-hydroxy-3-biphenylcarboxylic acid hydrochloride (1:1)
  • 5'-Chloro-2'-hydroxy-3-biphenylcarboxylic acid
  • 3'-amino-2'-hydroxy-4',6'-dimethoxyacetophenone
  • 5-Bromo-2-hydroxy-3-biphenylcarboxylic acid
  • Diflunisal
  • 1-amino-3-(3-methylpyridin-2-yl)oxypropan-2-ol
  • Tert-butyl 2-(2-amino-3,3-difluoropropyl)piperidine-1-carboxylate
  • tert-butyl N-[2-hydroxy-4-(prop-2-enoyl)phenyl]carbamate
  • N-methyl-N-[2-(2,4,5-trifluorophenyl)ethyl]hydroxylamine
  • 3-(4-Cyclopropyl-1,3-thiazol-5-yl)-1,1,1-trifluoropropan-2-one
  • 2-Amino-1-(2-methoxyquinolin-3-yl)propan-1-one
  • 5-chloro-1-methyl-4-[(2S)-oxiran-2-yl]-3-(trifluoromethyl)-1H-pyrazole
  • Methyl 3-(2-{[(tert-butoxy)carbonyl]amino}-5-hydroxyphenyl)-2-hydroxypropanoate
  • 1-(4,5,6,7-tetrahydro-1H-indol-2-yl)cyclopropan-1-ol
  • 4-[(1S)-2-amino-1-hydroxyethyl]-2-methoxy-6-nitrophenol
  • tert-butyl N-[5-(2-fluoro-1-hydroxyethyl)-2,3-dimethoxyphenyl]carbamate
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