(6R)-6-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3,6-dihydro-2H-1,4-oxazine

Names

[ CAS No. ]:
380499-07-0

[ Name ]:
(6R)-6-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3,6-dihydro-2H-1,4-oxazine

Chemical & Physical Properties

[ Molecular Formula ]:
C20H16F7NO2

[ Molecular Weight ]:
435.33500

[ Exact Mass ]:
435.10700

[ PSA ]:
30.82000

[ LogP ]:
5.22210

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (2R,3R)-2-[(1R)-1-(3,5-bis-trifluoro-methylphenyl)ethoxy]-3-(4-fluorophenyl)morpholine
  • (R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol

DownStream

  • (2R,3S)-2-[(1R)-1-[3,5-bis(Trifluoromethyl)phenyl)ethoxy]-3-(4-fluorophenyl)morpholine
  • (2R,3R)-2-[(1R)-1-(3,5-bis-trifluoro-methylphenyl)ethoxy]-3-(4-fluorophenyl)morpholine
  • Aprepitant

Related Compounds

  • 1-(2-Methoxypropyl)-1H-imidazol-2-amine
  • N-(3-hydroxy-4-methyl-phenyl)prop-2-enamide
  • 1,1a(2)-[1,1a(2)-Biphenyl]-4,4a(2)-diylbis[2-diazoethanone]
  • N-((2-(4-chlorophenyl)-4-methylthiazol-5-yl)methyl)propan-2-amine
  • 1-(2,2-Dimethylbutyl)-1H-imidazol-2-amine
  • N-((2-(4-chlorophenyl)-4-methylthiazol-5-yl)methyl)cyclopropanamine
  • 4,4',4''-((2,4,6-Trimethylbenzene-1,3,5-triyl)tris(methylene))tribenzonitrile
  • ethyl 4,5-diiodo-1H-imidazole-2-carboxylate
  • N-(m-Tolyl)benzothioamide
  • 1-(1-methylpiperidin-4-yl)-1H-imidazol-4-amine
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