Triptonide

Suppliers

Names

[ Name ]:
Triptonide

[Synonym ]:
l-triptonide
Triptolide,14-deoxy-14-oxo
Triptonide
(3bS,4aS,5aS,6aS,7aS,7bS,8aS,8bS)-6a-Isopropyl-8b-methyl-3b,4,4a,7a,7b,8b,9,10-octahydrotrisoxireno[6,7:8a,9:4b,5]phenanthro[1,2-c]furan-1,6(3H,6aH)-dione
Trisoxireno[6,7:8a,9:4b,5]phenanthro[1,2-c]furan-1,6(3H,6aH)-dione, 3b,4,4a,7a,7b,8b,9,10-octahydro-8b-methyl-6a-(1-methylethyl)-, (3bS,4aS,5aS,6aS,7aS,7bS,8aS,8bS)-
14-Deoxy-14-oxotriptolide
(3bS,4aS,5aS,6aS,7aS,7bS,8aS,8bS)-8b-methyl-6a-(propan-2-yl)-3b,4,4a,7a,7b,8b,9,10-octahydrotrisoxireno[6,7:8a,9:4b,5]phenanthro[1,2-c]furan-1,6(3H,6aH)-dione

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
581.1±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₀H₂₂O₆

[ Molecular Weight ]:
358.385

[ Flash Point ]:
257.8±30.2 °C

[ Exact Mass ]:
358.141632

[ PSA ]:
80.96000

[ LogP ]:
1.49

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.638

[ Storage condition ]:
2-8°C

Safety Information

[ Symbol ]:

GHS06, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H300 + H330-H361f

[ Precautionary Statements ]:
P201-P260-P284-P301 + P310 + P330-P304 + P340 + P310-P403 + P233

[ Hazard Codes ]:
T+

[ RIDADR ]:
2811.0

[ Hazard Class ]:
6.1

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Triptolide
Triptolide
(1R,2S,4aS,10aR)-1-((benzyloxy)methyl)-2-(hydroxymethyl)-7-isopropyl-4a-methyl-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-1,8-diol
(4bS,8aR)-8-((benzyloxy)methyl)-7-formyl-2-isopropyl-4b-methyl-4b,5,6,8a,9,10-hexahydrophenanthren-1-yl acetate
7β,14,19-trihydroxy-18(4->3)abeo-abieta-3,8,11,13-tetraen-18-oic acid lactone