4-Methoxy-4-oxobutanoic acid

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Names

[ CAS No. ]:
3878-55-5

[ Name ]:
4-Methoxy-4-oxobutanoic acid

[Synonym ]:
4-Methoxy-4-oxobutanoic acid
mono-Methyl succinate
Butanedioic acid, monomethyl ester
mono-Methyl hydrogen succinate
MFCD00002788
EINECS 223-408-2

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
259.2±0.0 °C at 760 mmHg

[ Melting Point ]:
54-57 °C(lit.)

[ Molecular Formula ]:
C5H8O4

[ Molecular Weight ]:
132.115

[ Flash Point ]:
104.5±16.1 °C

[ Exact Mass ]:
132.042252

[ PSA ]:
63.60000

[ LogP ]:
-0.21

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.436

[ Storage condition ]:
2~8°C

[ Stability ]:
Stable. Incompatible with strong oxidizing agents. Combustible.

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2917190090

Precursor & DownStream

Precursor

  • Dimethyl succinate
  • methyl 4-nitrobutyrate
  • Methanol
  • Succinic acid
  • Succinic anhydride
  • Methyl 2-methyl-2-propanyl succinate
  • Methyl 6-oxohexanoate
  • Maleic anhydride
  • fumaric acid
  • trioxane

DownStream

  • Methyl 3-bromopropanoate
  • cis-Vaccenic acid
  • Trepibutone
  • Octanedioic acid
  • Dimethyl adipate
  • 7-methoxy-7-oxoheptanoic acid
  • methyl 4-methylhexanoate
  • Methyl propanoate
  • methyl heptanoate-4,4-d2

Customs

[ HS Code ]: 2918990090

[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Phagocyte-like NADPH oxidase generates ROS in INS 832/13 cells and rat islets: role of protein prenylation.

Am. J. Physiol. Regul. Integr. Comp. Physiol. 300(3) , R756-62, (2011)

Recent evidence suggests that an acute increase in the generation of phagocyte-like NADPH-oxidase (Nox)-mediated reactive oxygen species (ROS) may be necessary for glucose-stimulated insulin secretion...

Stimulation of insulin release in vivo by the methyl esters of succinic acid and glutamic acid.

Adv. Exp. Med. Biol. 426 , 231-4, (1997)

Differences between mouse and rat pancreatic islets: succinate responsiveness, malic enzyme, and anaplerosis.

Am. J. Physiol. Endocrinol. Metab. 283(2) , E302-10, (2002)

Succinic acid methyl esters are potent insulin secretagogues in rat pancreatic islets, but they do not stimulate insulin release in mouse islets. Unlike rat and human islets, mouse islets lack malic e...


More Articles

Related Compounds

  • 3-amino-4-methoxy-4-oxobutanoic acid
  • 3-Benzyl-4-Methoxy-4-oxobutanoic acid
  • 2-Hydroxy-4-methoxy-4-oxobutanoic acid
  • 2-Hydroxy-4-methoxy-4-oxobutanoic acid
  • 3-Hydroxy-4-methoxy-4-oxobutanoic acid
  • 2-benzamido-4-methoxy-4-oxobutanoic acid