(E)-Guggulsterone
Suppliers
Names
[ CAS No. ]:
39025-24-6
[ Name ]:
(E)-Guggulsterone
[Synonym ]:
Z-guggulsterone
UNII:9B259YE66O
E-guggulsterone
Pregna-4,17-diene-3,16-dione, (17E)-
trans-Guggulsterone
Guggulsterone
(17E)-Pregna-4,17-diene-3,16-dione
Pregna-4,17(20)-diene-3,16-dione, (17E)-
(17E)-Pregna-4,17(20)-diene-3,16-dione
GUGGULSTERONE E
GS,TRANS
GUGGULESTERONE E
GUGGULSTERONE, (E)-
Z-Guggulsteron
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
463.3±45.0 °C at 760 mmHg
[ Melting Point ]:
170-171.5°
[ Molecular Formula ]:
C21H28O2
[ Molecular Weight ]:
312.446
[ Flash Point ]:
172.3±25.7 °C
[ Exact Mass ]:
312.208923
[ PSA ]:
34.14000
[ LogP ]:
3.65
[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C
[ Index of Refraction ]:
1.557
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H335
[ Precautionary Statements ]:
P261
[ Hazard Codes ]:
Xi
[ Risk Phrases ]:
37-52/53
[ Safety Phrases ]:
61-36
[ RIDADR ]:
NONH for all modes of transport
Articles
Biochim. Biophys. Acta 1844(9) , 1684-93, (2014)
Farnesoid X receptor (FXR) is a member of the nuclear receptor superfamily of transcription factors that plays a key role in the regulation of bile acids, lipid and glucose metabolisms. The regulative...
Int. Immunopharmacol. 26 , 194-202, (2015)
Guggulsterone (GS), a plant steroid and a compound found at high levels in Commiphora myrrha, exhibits anti-inflammatory, anti-cancer, and cholesterol-lowering effects. However, the potential of GS to...
Mol. Pharmacol. 87(5) , 878-89, (2015)
Constitutive androstane receptor (CAR) and pregnane X receptor (PXR) are xenobiotic sensors that enhance the detoxification and elimination of xenobiotics and endobiotics by modulating the expression ...