9-Methoxycamptothecine

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Names

[ Name ]:
9-Methoxycamptothecine

[Synonym ]:
1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-4-hydroxy-10-methoxy-, (4S)-
10-methoxycamptothecin
9-methoxycamtothecin
(4S)-4-Ethyl-4-hydroxy-10-methoxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
Camptothecin,9-methoxy

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
773.1±60.0 °C at 760 mmHg

[ Melting Point ]:
223-225 ºC

[ Molecular Formula ]:
C₂₁H₁₈N₂O₅

[ Molecular Weight ]:
378.378

[ Flash Point ]:
421.4±32.9 °C

[ Exact Mass ]:
378.121582

[ PSA ]:
90.65000

[ LogP ]:
2.00

[ Vapour Pressure ]:
0.0±2.8 mmHg at 25°C

[ Index of Refraction ]:
1.723

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
Slightly soluble (2.7 g/L) (25 ºC)

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

rubitecan
diazomethane
9-Hydroxycamptothecin
9-Aminocamptothecin
Campathecin

DownStream

Related Compounds

9-methoxycamptothecine
9-methoxy-5-methyl-2,6-dihydro-pyrido[4,3-b]carbazol-1-one
9-Methyl-9H-carbazole-3-sulfonyl chloride
9-Bromo-10-[4-(2-naphthyl)phenyl]anthracene
9-acetyloxyoctadec-12-enoic acid
9,10-dihydro-N-[3-(4-methoxyphenyl)propanoyl]-9,10-dimethyl-9,10-epoxyiminoanthracene
2-(3-(Hydroxymethyl)azetidin-1-yl)-1-(pyrazin-2-yl)ethanone
(1-((2,4-Dichloropyrimidin-5-yl)methyl)azetidin-3-yl)methanol
isopropyl N-hydroxyimidocarbamate
(1-((6-Chloropyridazin-3-yl)methyl)azetidin-3-yl)methanol
N-hydroxymethylacetamidine
3-Iodo-5-methoxypyridin-2-amine
2-(5,5-Dimethylpyrrolidin-2-YL)ethan-1-OL
3-(Cyclopropylamino)-3-(2,3-dihydrobenzo[b][1,4]dioxin-5-yl)propan-1-ol
(3-(Methylthio)pyrrolidin-1-yl)(phenyl)methanone
3-(Cyclopropylamino)-3-(thiophen-2-yl)propan-1-ol

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