9-Methoxycamptothecine

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Names

[ CAS No. ]:
39026-92-1

[ Name ]:
9-Methoxycamptothecine

[Synonym ]:
1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-4-hydroxy-10-methoxy-, (4S)-
10-methoxycamptothecin
9-methoxycamtothecin
(4S)-4-Ethyl-4-hydroxy-10-methoxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
Camptothecin,9-methoxy

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
773.1±60.0 °C at 760 mmHg

[ Melting Point ]:
223-225 ºC

[ Molecular Formula ]:
C21H18N2O5

[ Molecular Weight ]:
378.378

[ Flash Point ]:
421.4±32.9 °C

[ Exact Mass ]:
378.121582

[ PSA ]:
90.65000

[ LogP ]:
2.00

[ Vapour Pressure ]:
0.0±2.8 mmHg at 25°C

[ Index of Refraction ]:
1.723

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
Slightly soluble (2.7 g/L) (25 ºC)

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • rubitecan
  • diazomethane
  • 9-Hydroxycamptothecin
  • 9-Aminocamptothecin
  • Campathecin

DownStream

Related Compounds

  • 9-methoxycamptothecine
  • 9-methoxy-5-methyl-2,6-dihydro-pyrido[4,3-b]carbazol-1-one
  • 9-Methyl-9H-carbazole-3-sulfonyl chloride
  • 9-Bromo-10-[4-(2-naphthyl)phenyl]anthracene
  • 9-acetyloxyoctadec-12-enoic acid
  • 9,10-dihydro-N-[3-(4-methoxyphenyl)propanoyl]-9,10-dimethyl-9,10-epoxyiminoanthracene
  • Ethyl 6-(dimethoxymethyl)-2-(methylthio)pyrimidine-4-carboxylate
  • Ethyl 2-amino-6-(dimethoxymethyl)pyrimidine-4-carboxylate
  • Ethyl 6-formyl-2-(methylthio)pyrimidine-4-carboxylate
  • Ethyl 2-(dimethylamino)-6-formylpyrimidine-4-carboxylate
  • Ethyl 2-tert-butyl-6-formylpyrimidine-4-carboxylate
  • 2-Methoxy-6-(trifluoromethyl)pyrimidine-4-carbaldehyde
  • Ethyl 2-chloro-5,6,7,8-tetrahydropyrido[4,3-D]pyrimidine-4-carboxylate
  • Ethyl 2-methyl-5,6,7,8-tetrahydropyrido[4,3-D]pyrimidine-4-carboxylate
  • Benzyl (2-(5-aminopyrimidin-2-yl)ethyl)carbamate
  • 2-(2-(((Benzyloxy)carbonyl)amino)ethyl)pyrimidine-5-carboxylic acid
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