Dihydrocytochalasin B

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Names

[ CAS No. ]:
39156-67-7

[ Name ]:
Dihydrocytochalasin B

[Synonym ]:
2,3-Dihydro-cytochalasin B
21,22-dihydro-phomin
EINECS 254-324-4
21,22-Dihydrocytochalalsin B
CYTOCHALASIN B,DIHYDRO
21,22-dihydro-cytochalasin-B
dihydrocytocholasin-B
7(S),20(R)-dihydroxy-16(R)-methyl-10-phenyl-24-oxa[14]cytochalasa-6(12),13(E)-diene-1,23-dione
DHCB
(7S,13E,16R,20R)-7,20-Dihydroxy-16-methyl-10-phenyl-24-oxa[14]cytochalasa-6(12),13-diene-1,23-dione
MFCD00010541

Chemical & Physical Properties

[ Density]:
1.194g/cm3

[ Boiling Point ]:
727.474ºC at 760 mmHg

[ Melting Point ]:
203-205ºC

[ Molecular Formula ]:
C29H39NO5

[ Molecular Weight ]:
481.62400

[ Flash Point ]:
393.762ºC

[ Exact Mass ]:
481.28300

[ PSA ]:
95.86000

[ LogP ]:
4.04490

[ Index of Refraction ]:
1.584

[ Storage condition ]:
-20℃

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS06, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H300-H310-H330-H351

[ Precautionary Statements ]:
P260-P264-P280-P284-P302 + P350-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ Hazard Codes ]:
T+,T

[ Risk Phrases ]:
26/27/28-40

[ Safety Phrases ]:
22-36/37/39-45

[ RIDADR ]:
UN 2811 6.1/PG 2

[ Hazard Class ]:
6.1(a)

Articles

Tetraploidization increases sensitivity to Aurora B kinase inhibition.

Cell Cycle 11(13) , 2567-77, (2012)

Aurora kinases are overexpressed in many cancers and are targets for anticancer drugs. The yeast homolog of Aurora B kinase, IPL1, was found to be a ploidy-specific lethality gene. Given that polyploi...

Centrifugal and chromatographic analyses of tryptophan and tyrosine uptake by red blood cells and GLUT1 proteoliposomes with permeability estimates and observations on dihydrocytochalasin B.

J. Biochem. Biophys. Methods 55(2) , 127-40, (2003)

We analyzed transport into liposomes and proteoliposomes, separated the free and internalized radioactively labeled substrates by size-exclusion chromatography (SEC) and observed a net influx owing to...

Degradation and recycling of the substrate-binding subunit of type II iodothyronine 5'-deiodinase in astrocytes.

J. Biol. Chem. 271(27) , 16369-74, (1996)

Thyroxine dynamically regulates levels of type II iodothyronine 5'-deiodinase (5'D-II) by modulating enzyme inactivation and targeting the enzyme to different pathways of internalization. 5'D-II is an...


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