(4-Biphenyl)Acetamide

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Names

[ CAS No. ]:
4075-79-0

[ Name ]:
(4-Biphenyl)Acetamide

[Synonym ]:
N-[1,1'-biphenyl]-4-ylacetamide
4-acetylaminobiphenyl
N-(4-Biphenylyl)acetamide
N-(4-phenylphenyl)acetamide
N-BIPHENYL-4-YL-ACETAMIDE
Acetamide, N-[1,1'-biphenyl]-4-yl-

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
419.3±24.0 °C at 760 mmHg

[ Melting Point ]:
172ºC

[ Molecular Formula ]:
C14H13NO

[ Molecular Weight ]:
211.259

[ Flash Point ]:
251.4±7.8 °C

[ Exact Mass ]:
211.099716

[ PSA ]:
29.10000

[ LogP ]:
3.14

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.610

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AE6125000
CHEMICAL NAME :
Acetanilide, 4'-phenyl-
CAS REGISTRY NUMBER :
4075-79-0
BEILSTEIN REFERENCE NO. :
2097736
LAST UPDATED :
199701
DATA ITEMS CITED :
9
MOLECULAR FORMULA :
C14-H13-N-O
MOLECULAR WEIGHT :
211.28
WISWESSER LINE NOTATION :
1VMR DR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2770 mg/kg/21W-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Sense Organs and Special Senses (Ear) - effect, not otherwise specified Skin and Appendages - tumors
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
13 gm/kg/3Y-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors Kidney, Ureter, Bladder - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4070 mg/kg/34W-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Sense Organs and Special Senses (Ear) - effect, not otherwise specified Skin and Appendages - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3425 mg/kg/26W-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2240 mg/kg/16W-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Sense Organs and Special Senses (Ear) - effect, not otherwise specified Skin and Appendages - tumors

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
10 ug/plate
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 175,11,1986 *** REVIEWS *** TOXICOLOGY REVIEW ADCSAJ Advances in Chemistry Series. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) No.1- 1950- Volume(issue)/page/year: 13,271,1970

Safety Information

[ HS Code ]:
2924299090

Synthetic Route

Precursor & DownStream

Precursor

  • 4-Bromoacetanilide
  • Phenylboronic acid
  • Ethanoic anhydride
  • 4-Aminobiphenyl
  • Acetamide
  • 4-Bromobiphenyl
  • 4-acetamidophenyl trifluoromethanesulfonate
  • Sodium tetraphenylborate
  • (NE)-N-[1-(4-phenylphenyl)ethylidene]hydroxylamine

DownStream

  • 2-bromo-1,1':4',1''-terphenyl
  • para-Terphenyl
  • 4-Amino-p-terphenyl
  • 6-phenylquinoline
  • 4,4''-Dinitro-p-terphenyl
  • [1,1'-Biphenyl]-4-sulfonicacid, 4'-amino-
  • N-Methyl-4-biphenylamine
  • 2'-NITRO-[1,1'-BIPHENYL]-4-CARBOXYLIC ACID
  • Bis(4-biphenylyl)amine
  • [1,1'-Biphenyl]-4-ol,4-acetate

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%


Related Compounds

  • 4-biphenyl-N,N-dimethylsulfamate
  • 4-BIPHENYL-3'-ACETYL-CARBOXYLICACID
  • 4-(biphenyl-4-yl)but-3-yn-1-ol
  • 4-BIPHENYL-(3'-ETHOXY)CARBOXYLICACID
  • N-(4-BIPHENYL-4-YL-THIAZOL-2-YL)-2-CHLORO-ACETAMIDE
  • N-acetyl-N-(4-oxo-2-sulfanylidene-thiazolidin-3-yl)acetamide