D-3-Deoxyglucosone

Suppliers

Names

[ Name ]:
D-3-Deoxyglucosone

[Synonym ]:
3-Deoxy-D-erythro-hexos-2-ulose
3-Deoxyglucosone
3-Deoxy-D-erythro-hexosulose
(4S,5R)-4,5,6-trihydroxy-2-oxohexanal
D-erythro-Hexos-2-ulose, 3-deoxy-

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
400.1±45.0 °C at 760 mmHg

[ Melting Point ]:
73-75ºC

[ Molecular Formula ]:
C₆H₁₀O₅

[ Molecular Weight ]:
162.141

[ Flash Point ]:
209.9±25.2 °C

[ Exact Mass ]:
162.052826

[ PSA ]:
94.83000

[ LogP ]:
-2.38

[ Vapour Pressure ]:
0.0±2.1 mmHg at 25°C

[ Index of Refraction ]:
1.512

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MQ3390000

CHEMICAL NAME :: D-erythro-Hexosulose, 3-deoxy-

CAS REGISTRY NUMBER :: 4084-27-9

LAST UPDATED :: 199712

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C6-H10-O5

MOLECULAR WEIGHT :: 162.16

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Cytogenetic analysis

TEST SYSTEM :: Rodent - hamster Lung

DOSE/DURATION :: 2 gm/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 227,117,1989

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

Articles

3-Deoxyglucosone: a potential glycating agent accountable for structural alteration in H3 histone protein through generation of different AGEs.

PLoS ONE 10(2) , e0116804, (2015)

Advanced glycation end-products (AGEs) are heterogeneous group of compounds, known to be implicated in diabetic complications. One of the consequences of the Maillard reaction is attributed to the pro...

Studies on the Formation of Maillard and Caramelization Products from Glucosamine Incubated at 37 °C.

J. Agric. Food Chem. 63 , 6249-61, (2015)

This experiment compared the in vitro degradation of glucosamine (GlcN), N-acetylglucosamine, and glucose in the presence of NH3 incubated at 37 °C in phosphate buffer from 0.5 to 12 days. The reactio...

GC-MS Method for the Quantitation of Carbohydrate Intermediates in Glycation Systems.

J. Agric. Food Chem. 63 , 5911-9, (2015)

Glycation is a ubiquitous nonenzymatic reaction of carbonyl compounds with amino groups of peptides and proteins, resulting in the formation of advanced glycation end-products (AGEs) and thereby affec...