R-(-)-Apomorphine

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Names

[ Name ]:
R-(-)-Apomorphine

[Synonym ]:
(R)-Apomorphine Hydrochloride Hemihydrate
EINECS 206-243-0
R-(-)-Apomorphine
Apomorphine hydrochloride hemihydrate
MFCD00150904
R-(−)-Apomorphine hydrochloride hemihydrate
Apomorphine (hydrochloride hemihydrate)

Chemical & Physical Properties

[ Density]:
1.299 g/cm3

[ Boiling Point ]:
473.4ºC at 760 mmHg

[ Melting Point ]:
285-287 °C(lit.)

[ Molecular Formula ]:
C₁₇H₂₀ClNO₃

[ Molecular Weight ]:
321.79900

[ Flash Point ]:
268.8ºC

[ Exact Mass ]:
321.11300

[ PSA ]:
52.93000

[ LogP ]:
3.52550

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301

[ Precautionary Statements ]:
P301 + P310

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R22

[ Safety Phrases ]:
S36

[ RIDADR ]:
UN 2811 6.1/PG 3

[ WGK Germany ]:
3

Articles

Modulation of 5-lipoxygenase in proteotoxicity and Alzheimer's disease.

J. Neurosci. 33(25) , 10512-25, (2013)

The accumulation of intracellular β amyloid (Aβ) may be one of the factors leading to neuronal cell death in Alzheimer's disease (AD). Using a pyrazole called CNB-001, which was selected for its abili...

Activation of serotonin2A receptors in the medial septum-diagonal band of Broca complex enhanced working memory in the hemiparkinsonian rats.

Neuropharmacology 91 , 23-33, (2015)

Serotonin2A (5-HT2A) receptors are highly expressed in the medial septum-diagonal band of Broca complex (MS-DB), especially in parvalbumin (PV)-positive neurons linked to hippocampal theta rhythm, whi...

Effects of prolonged neuronal nitric oxide synthase inhibition on the development and expression of L-DOPA-induced dyskinesia in 6-OHDA-lesioned rats.

Neuropharmacology 89 , 87-99, (2014)

It is well known that nitric oxide (NO) interacts with dopamine (DA) within the striatal circuitry. The anti-dyskinetic properties of NO synthase (NOS) inhibitors demonstrate the importance of NO in L...

(6aR)-10,11-Dimethoxy-4,5,6a,7-tetrahydro-6-methyl-6H-dibenzo[de,g]quinoline
(R)-MDO-Apomorphine
(R)-2-(2-Chloro-5-(trifluoromethyl)phenyl)pyrrolidine hydrochloride
(R)-2-(3-chlorophenyl)piperidine hydrochloride
(R-(R*,R*))-N-(2-Hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl)-2-o xoacetamide
(R)-(+)-S-methyl tert-butylphenylphosphinothiolate
1-{[1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]methyl}cyclopropan-1-ol
tert-butyl N-[1-(4-aminobutan-2-yl)cyclohexyl]carbamate
1-(3-Cyano-4-fluorophenyl)-2,2-dimethylcyclopropane-1-carboxylic acid
3-(3-tert-butyl-1H-pyrazol-4-yl)-2,2-dimethylpropanoic acid
1-(2-Methylbut-3-yn-2-yl)-3-(trifluoromethyl)benzene
1,1-Difluoro-2-methyl-3-[2-(trifluoromethyl)pyridin-3-yl]propan-2-amine
4-(1-Amino-4,4-difluorocyclohexyl)-2-nitrophenol
2-(1-Bromopropan-2-yl)-1,3-difluoro-4-nitrobenzene
2-{1-[3-Chloro-4-(trifluoromethyl)phenyl]cyclopropyl}acetic acid
5-(1,2,2,2-Tetrafluoroethyl)-1,2-oxazole-3-carboxylic acid

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