2,4-Dibromothiazole

Names

[ CAS No. ]:
4175-77-3

[ Name ]:
2,4-Dibromothiazole

[Synonym ]:
2,4-Dibromo-1,3-thiazole
2,4-Dibromothiazole
Thiazole, 2,4-dibromo-
MFCD01318994
2,4- Dibromo thiazole

Chemical & Physical Properties

[ Density]:
2.3±0.1 g/cm3

[ Boiling Point ]:
242.8±13.0 °C at 760 mmHg

[ Melting Point ]:
80-84°C

[ Molecular Formula ]:
C₃HBr₂NS

[ Molecular Weight ]:
242.92

[ Flash Point ]:
100.6±19.8 °C

[ Exact Mass ]:
240.819626

[ PSA ]:
41.13000

[ LogP ]:
2.70

[ Vapour Pressure ]:
0.1±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.650

[ Storage condition ]:
Keep Cold

MSDS

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H315-H318-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R22;R37/38;R41

[ Safety Phrases ]:
S26-S39

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2934100090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

2-Bromo-5-(tributylstannyl)thiazole
4-Bromo-2-(4-methoxyphenyl)thiazole
4-Bromothiazole
4-Bromo-2-phenylthiazole
4-Bromo-2-isopropylthiazole
2-acetyl-4-bromothiazole
Thiazole
4-Bromo-1,3-thiazole-2-carboxylic acid
2-(4-Bromothiazol-2-yl)propan-2-ol
2,4-Dibromothiazole-5-carboxylic acid

Customs

[ HS Code ]: 2934100090

[ Summary ]:
2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Articles

A concise total synthesis of melithiazole C.

Org. Lett. 9 , 3425, (2007)

A short and convergent synthesis of the myxobacterial antibiotic melithiazole C is described featuring a highly E-selective cross-metathesis as the key step.