2,4-Dibromothiazole

Modify Date: 2024-01-02 11:23:55

2,4-Dibromothiazole Structure
2,4-Dibromothiazole structure
Common Name 2,4-Dibromothiazole
CAS Number 4175-77-3 Molecular Weight 242.92
Density 2.3±0.1 g/cm3 Boiling Point 242.8±13.0 °C at 760 mmHg
Molecular Formula C3HBr2NS Melting Point 80-84°C
MSDS Chinese USA Flash Point 100.6±19.8 °C
Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger

 Use of 2,4-Dibromothiazole


2,4-Dibromothiazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

 Names

Name 2,4-Dibromothiazole
Synonym More Synonyms

 2,4-Dibromothiazole Biological Activity

Description 2,4-Dibromothiazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Related Catalog
In Vitro 2,4-二溴噻唑用作合成 Melithiazole C 的结构单元,采用高度 (E)-选择性的衍生 4-乙烯基噻唑和二烯侧链之间的交叉复分解。它还用作制备各种具有生物活性特性的 2,4-分布式噻唑衍生物的中间体,例如运动神经元存活 (SMN) 蛋白调节剂。

 Chemical & Physical Properties

Density 2.3±0.1 g/cm3
Boiling Point 242.8±13.0 °C at 760 mmHg
Melting Point 80-84°C
Molecular Formula C3HBr2NS
Molecular Weight 242.92
Flash Point 100.6±19.8 °C
Exact Mass 240.819626
PSA 41.13000
LogP 2.70
Vapour Pressure 0.1±0.5 mmHg at 25°C
Index of Refraction 1.650
Storage condition Keep Cold

 Safety Information

Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger
Hazard Statements H302-H315-H318-H335
Precautionary Statements P261-P280-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xn:Harmful
Risk Phrases R22;R37/38;R41
Safety Phrases S26-S39
RIDADR NONH for all modes of transport
HS Code 2934100090

 Synthetic Route

~98%

2,4-Dibromothiazole Structure

2,4-Dibromothiazole

CAS#:4175-77-3

Literature: Stanetty, Peter; Schnuerch, Michael; Mihovilovic, Marko D. Journal of Organic Chemistry, 2006 , vol. 71, # 10 p. 3754 - 3761

~57%

2,4-Dibromothiazole Structure

2,4-Dibromothiazole

CAS#:4175-77-3

Literature: GALAPAGOS N.V. Patent: WO2007/138072 A2, 2007 ; Location in patent: Page/Page column 80 ;

~%

2,4-Dibromothiazole Structure

2,4-Dibromothiazole

CAS#:4175-77-3

Literature: American Cyanamid Company Patent: US4990520 A1, 1991 ; US 4990520 A

~%

2,4-Dibromothiazole Structure

2,4-Dibromothiazole

CAS#:4175-77-3

Literature: Athmani, Salah; Bruce, Andrew; Iddon, Brian Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 2 p. 215 - 219

 Customs

HS Code 2934100090
Summary 2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

 Articles1

More Articles
A concise total synthesis of melithiazole C.

Org. Lett. 9 , 3425, (2007)

A short and convergent synthesis of the myxobacterial antibiotic melithiazole C is described featuring a highly E-selective cross-metathesis as the key step.

 Synonyms

2,4-Dibromo-1,3-thiazole
2,4-Dibromothiazole
Thiazole, 2,4-dibromo-
MFCD01318994
2,4- Dibromo thiazole
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