N-(4-Nitrophenyl)-L-leucinamide
Suppliers
Names
[ CAS No. ]:
4178-93-2
[ Name ]:
N-(4-Nitrophenyl)-L-leucinamide
[Synonym ]:
MFCD00063681
EINECS 224-047-3
Pentanamide, 2-amino-4-methyl-N-(4-nitrophenyl)-, (2S)-
N-(4-Nitrophenyl)-L-leucinamide
h-leu-pna
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
454.5±30.0 °C at 760 mmHg
[ Melting Point ]:
88-90ºC
[ Molecular Formula ]:
C12H17N3O3
[ Molecular Weight ]:
251.282
[ Flash Point ]:
228.7±24.6 °C
[ Exact Mass ]:
251.126984
[ PSA ]:
100.94000
[ LogP ]:
1.83
[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C
[ Index of Refraction ]:
1.589
[ Storage condition ]:
2-8°C
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H317-H319
[ Precautionary Statements ]:
P280-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves
[ Hazard Codes ]:
Xi
[ Risk Phrases ]:
R36
[ Safety Phrases ]:
S26-S36-S37
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ HS Code ]:
2924299090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2924299090
[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
Articles
PLoS ONE 10(2) , e0115859, (2015)
Malaria is a parasitic disease that remains a global health burden. The ability of the parasite to rapidly develop resistance to therapeutics drives an urgent need for the delivery of new drugs. The M...
Pharmacol. Res. Commun. 16(6) , 533-8, (1984)
Beta-phenyl cysteine: a leucine aminopeptidase inhibitor. The kinetic parameters of the inhibition of the leucine aminopeptidase by beta-phenyl cysteine are reported in this communication.
Mol. Divers. 17(1) , 123-37, (2013)
Aminopeptidase N (APN) inhibitors have been reported to be effective in treating of life threatening diseases including cancer. Validated ligand- and structure-based pharmacophore mapping approaches w...