LCS-1

Suppliers

Names

[ CAS No. ]:
41931-13-9

[ Name ]:
LCS-1

[Synonym ]:
4,5-dichloro-2-m-tolyl-2H-pyridazin-3-one
4,5-Dichlor-2-m-tolyl-pyridazin-3-on
4,5-Dichloro-2-(3-methylphenyl)-3(2H)-pyridazinone
pyridazinone,2-46
4,5-Dichloro-2-m-tolylpyridazin-3(2H)-one

Chemical & Physical Properties

[ Density]:
1.39g/cm3

[ Boiling Point ]:
339.6ºC at 760 mmHg

[ Molecular Formula ]:
C11H8Cl2N2O

[ Molecular Weight ]:
255.10000

[ Flash Point ]:
159.2ºC

[ Exact Mass ]:
254.00100

[ PSA ]:
34.89000

[ LogP ]:
2.84770

[ Appearance of Characters ]:
white to beige

[ Index of Refraction ]:
1.627

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
DMSO: soluble10mg/mL (clear solutikon, warmed)

MSDS

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H319

[ Precautionary Statements ]:
P301 + P310-P305 + P351 + P338

[ Hazard Codes ]:
T,Xi

[ Risk Phrases ]:
25-36

[ Safety Phrases ]:
26-45

[ RIDADR ]:
UN 2811 6.1 / PGIII

[ HS Code ]:
2933990090

Synthetic Route

Precursor & DownStream

Precursor

  • M-TOLYLHYDRAZINE
  • 3,4-Dichloro-5-hydroxy-2(5H)-furanone

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Nrf2/p62 signaling in apoptosis resistance and its role in cadmium-induced carcinogenesis.

J. Biol. Chem. 289(41) , 28660-75, (2014)

The cadmium-transformed human lung bronchial epithelial BEAS-2B cells exhibit a property of apoptosis resistance as compared with normal non-transformed BEAS-2B cells. The level of basal reactive oxyg...


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Related Compounds

  • LCS-1.34
  • Propane,1,1-bis(ethylsulfonyl)-2-methyl-
  • Pyridinium, 1- (2-hydroxy[1,1:3,1-terphenyl]-5-yl)-2,4, 6-triphenyl-, perchlorate (salt)
  • Cyclohexanecarboxylicacid, 1-methyl-3-oxo-, ethyl ester
  • 2-[1-(2-hydroxy-3,5-dimethylphenyl)cyclohexyl]-4,6-dimethylphenol
  • 3-[1-(2,5-dimethylthiophen-3-yl)octadecyl]-4-propan-2-ylideneoxolane-2,5-dione
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-(3-methoxy-1-methyl-1H-pyrazole-4-carbonyl)-N-(2-methylbenzo[d]thiazol-5-yl)piperidine-4-carboxamide
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-[4-(4-Methoxyphenyl)sulfonylpiperazin-1-yl]-4-oxopyrido[1,2-a]pyrimidine-3-carbaldehyde
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • 2-bromo-N-[4-methoxy-3-(1H-tetrazol-1-yl)phenyl]benzamide
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • (2R)-2-[[(1R)-1-Phenyl-2-hydroxyethyl]amino]-3,3,3-trifluoro-1-propanol