(S)-(-)-PROPRANOLOL HYDROCHLORIDE

Suppliers

Names

[ Name ]:
(S)-(-)-PROPRANOLOL HYDROCHLORIDE

[Synonym ]:
dl-propranololHClbp
PROPRANOLOL HCL
dl-propranolol hcl
dl-propranololhydrochloridebp
PENTAPROPANOLOLHYDROCHLORIDE
Sazetidine A dihydrochloride
DL-PROPRANOLOL HYDROCHLORIDE
EINECS 224-096-0
PROPANOLOL HYDROCHLORIDE
L-Propranololhydrochlorid
MFCD00064547

Chemical & Physical Properties

[ Boiling Point ]:
434.9ºC at 760mmHg

[ Melting Point ]:
193-195ºC(lit.)

[ Molecular Formula ]:
C₁₆H₂₂ClNO₂

[ Molecular Weight ]:
295.80400

[ Flash Point ]:
216.8ºC

[ Exact Mass ]:
295.13400

[ PSA ]:
41.49000

[ LogP ]:
3.77040

[ Appearance of Characters ]:
powder

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
ethanol: 10 mg/mL

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H312-H332

[ Precautionary Statements ]:
P280

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2906199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

1-Naphthalenol
(S)-Glycidyl nosylate
isopropylamine
(S)-1-(isopropylamino)-3-(naphthyloxy)propan-2-ol
(R)-(-)-1-chloro-2-acetoxy-3-(1-naphthyloxy)propane
(S)-2-(benzyloxy)-3-chloro-N-isopropylpropan-1-amine
(S)-2-benzyloxy-3-isopropylamino-1-propanol
(S)-3-(naphthalen-1-yloxy)propane-1,2-diol

DownStream

Customs

[ HS Code ]: 2922509090

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

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Nat. Chem. Biol. 3(5) , 268-273, (2007)

The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain canc...

Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Nat. Chem. Biol. 5 , 765-71, (2009)

Studies of gene function and molecular mechanisms in Plasmodium falciparum are hampered by difficulties in characterizing and measuring phenotypic differences between individual parasites. We screened...

The Alpha-1D Is the Predominant Alpha-1-Adrenergic Receptor Subtype in Human Epicardial Coronary Arteries

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Objectives The goal was to identify alpha-1-adrenergic receptor (AR) subtypes in human coronary arteries.