2-Chlorotrityl Chloride

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Names

[ CAS No. ]:
42074-68-0

[ Name ]:
2-Chlorotrityl Chloride

[Synonym ]:
Benzene, 1-chloro-2-(chlorodiphenylmethyl)-
MFCD00161760
2-Chlorotritylchloride Polymer Resin
2-Chlorotrityl Chloride
(Chloro(2-chlorophenyl)methylene)dibenzene
EINECS 255-647-3
(2-Chlorophenyl)diphenylmethyl Chloride
Chloro(2-chlorophenyl)diphenylmethane
o-chlorphenyl-diphenyl-chloromethane(clotrimazole intermediate )
1-Chloro-2-[chloro(diphenyl)methyl]benzene
Clotrimazole Impurity 3
2-Chlorotrityl Chloride Resin

Chemical & Physical Properties

[ Density]:
1.222±0.06 g/cm3

[ Boiling Point ]:
421.3±40.0 °C at 760 mmHg

[ Melting Point ]:
136 ºC (benzene )

[ Molecular Formula ]:
C19H14Cl2

[ Molecular Weight ]:
313.22

[ Flash Point ]:
194.2±20.9 °C

[ Exact Mass ]:
312.047241

[ LogP ]:
6.16

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.614

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
Insuluble (1.1E-4 g/L) (25 ºC)

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26

[ RIDADR ]:
3261.0

[ WGK Germany ]:
3

[ HS Code ]:
2903999090

Synthetic Route

Precursor & DownStream

Precursor

  • MDK-4025
  • Methyl 2-chlorobenzoate
  • 1-Chloro-2-(trichloromethyl)benzene
  • benzene

DownStream

  • Clotrimazole
  • 2-[(2-chlorophenyl)-diphenylmethoxy]pyridine
  • 1-[(2-chlorophenyl)-diphenylmethyl]pyridin-4-one
  • 1-chloro-2-(1,1,2,2-tetraphenylethyl)benzene

Customs

[ HS Code ]: 2903999090

[ Summary ]:
2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

Formulation of highly functionalizable DNA nanoparticles based on 1,2-dithiolane derivatives.

ChemBioChem. 16(5) , 792-804, (2015)

We describe the formulation of synthetic virus models based on ionic compounds bearing the polymerizable 1,2-dithiolane moiety. First, cationic amphiphiles containing the polymeric inducer were prepar...

The influence of linker length on the properties of cathepsin S cleavable177Lu-labeled HPMA copolymers for pancreatic cancer imaging

Biomaterials 35(22) , 5760-70, (2014)

N-(2-hydroxypropyl)-methacrylamide (HPMA) copolymers have shown promise for application in the detection and staging of cancer. However, non-target accumulation, particularly in the liver and spleen, ...

Inhibitors of Matriptase-2 Based on the Trypsin Inhibitor SFTI-1.

ChemBioChem. 16 , 1601-7, (2015)

A series of 17 new analogues of trypsin inhibitor SFTI-1 were designed and synthesized to obtain matriptase-2 inhibitors. A number of the modified bicyclic peptides displayed much higher affinity towa...


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Related Compounds

  • 2-Chlorotrityl Chloride Resin
  • lead,oxygen(2-),chloride
  • 3-nitro-phthalic acid-1-ethyl ester-2-chloride
  • benzylbis(triphenylphosphine)palladium(ii) chloride
  • Clotrimazole
  • 2-dichlorophosphinothioylacetyl chloride