2-Chlorotrityl Chloride
2-Chlorotrityl Chloride structure
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Common Name | 2-Chlorotrityl Chloride | ||
|---|---|---|---|---|
| CAS Number | 42074-68-0 | Molecular Weight | 313.22 | |
| Density | 1.222±0.06 g/cm3 | Boiling Point | 421.3±40.0 °C at 760 mmHg | |
| Molecular Formula | C19H14Cl2 | Melting Point | 136 ºC (benzene ) | |
| MSDS | Chinese USA | Flash Point | 194.2±20.9 °C | |
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Formulation of highly functionalizable DNA nanoparticles based on 1,2-dithiolane derivatives.
ChemBioChem. 16(5) , 792-804, (2015) We describe the formulation of synthetic virus models based on ionic compounds bearing the polymerizable 1,2-dithiolane moiety. First, cationic amphiphiles containing the polymeric inducer were prepared and used to efficiently condense a DNA plasmid (pDNA) in... |
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The influence of linker length on the properties of cathepsin S cleavable177Lu-labeled HPMA copolymers for pancreatic cancer imaging
Biomaterials 35(22) , 5760-70, (2014) N-(2-hydroxypropyl)-methacrylamide (HPMA) copolymers have shown promise for application in the detection and staging of cancer. However, non-target accumulation, particularly in the liver and spleen, hinders the detection of resident or nearby metastatic lesi... |
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Inhibitors of Matriptase-2 Based on the Trypsin Inhibitor SFTI-1.
ChemBioChem. 16 , 1601-7, (2015) A series of 17 new analogues of trypsin inhibitor SFTI-1 were designed and synthesized to obtain matriptase-2 inhibitors. A number of the modified bicyclic peptides displayed much higher affinity towards matriptase-2 than towards the highly homologous matript... |
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Unraveling the interplay of backbone rigidity and electron rich side-chains on electron transfer in peptides: the realization of tunable molecular wires.
J. Am. Chem. Soc. 136(35) , 12479-88, (2014) Electrochemical studies are reported on a series of peptides constrained into either a 310-helix (1-6) or β-strand (7-9) conformation, with variable numbers of electron rich alkene containing side chains. Peptides (1 and 2) and (7 and 8) are further constrain... |
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Conformational ensembles explored dynamically from disordered peptides targeting chemokine receptor CXCR4.
Int. J. Mol. Sci. 16 , 12159-73, (2015) This work reports on the design and the synthesis of two short linear peptides both containing a few amino acids with disorder propensity and an allylic ester group at the C-terminal end. Their structural properties were firstly analyzed by means of experimen... |
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Twins in spirit - episode I: comparative preclinical evaluation of [(68)Ga]DOTATATE and [(68)Ga]HA-DOTATATE.
EJNMMI Res. 5 , 22, (2015) Recently, an intra-patient comparison demonstrated that the somatostatin (sst) ligand [(68)Ga]HA-DOTATATE ([(68)Ga]DOTA-3-iodo-Tyr(3)-octreotate) provides PET images comparable to or superior to those obtained with [(68)Ga]DOTATATE. To provide a comprehensive... |
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EDB Fibronectin Specific Peptide for Prostate Cancer Targeting.
Bioconjug. Chem. 26 , 830-8, (2015) Extradomain-B fibronectin (EDB-FN), one of the oncofetal fibronectin (onfFN) isoforms, is a high-molecular-weight glycoprotein that mediates cell adhesion and migration. The expression of EDB-FN is associated with a number of cancer-related biological process... |
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Picomolar Inhibition of Plasmepsin V, an Essential Malaria Protease, Achieved Exploiting the Prime Region.
PLoS ONE 10 , e0142509, (2015) Malaria is an infectious disease caused by Plasmodium parasites. It results in an annual death-toll of ~ 600,000. Resistance to all medications currently in use exists, and novel antimalarial drugs are urgently needed. Plasmepsin V (PmV) is an essential Plasm... |
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Collagen-mimetic peptide-modifiable hydrogels for articular cartilage regeneration.
Biomaterials 54 , 213-25, (2015) Regenerative medicine strategies for restoring articular cartilage face significant challenges to recreate the complex and dynamic biochemical and biomechanical functions of native tissues. As an approach to recapitulate the complexity of the extracellular ma... |
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Synthesis and characterization of a new Peptide prodrug of glucosamine with enhanced gut permeability.
PLoS ONE 10 , e0126786, (2015) The aim of this study was to synthesize a peptide prodrug of glucosamine (GlcN) with increased gut permeability through the gut peptide transporter 1 (PepT1). Glycine-Valine ester derivative of GlcN (GVG) was synthesised using solid phase synthesis followed b... |