(R)-2-AMINO-3-(5-HYDROXY-1H-INDOL-3-YL)PROPANOIC ACID

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Names

[ CAS No. ]:
4350-07-6

[ Name ]:
(R)-2-AMINO-3-(5-HYDROXY-1H-INDOL-3-YL)PROPANOIC ACID

[Synonym ]:
(2R)-2-amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid
Tryptophan,5-hydroxy-,D
D-5-HTP (D-2-Amino-3-(5-hydroxyindolyl)propionic acid
C11H12N2O3
5-Hydroxytryptophan D-form
HRP
D-Tryptophan,5-hydroxy
D-5-Hydroxytryptophan

Chemical & Physical Properties

[ Melting Point ]:
27ºC

[ Molecular Formula ]:
C11H12N2O3

[ Molecular Weight ]:
220.22500

[ Exact Mass ]:
220.08500

[ PSA ]:
99.34000

[ LogP ]:
1.52820

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YN7050000
CHEMICAL NAME :
Tryptophan, 5-hydroxy-, D-
CAS REGISTRY NUMBER :
4350-07-6
LAST UPDATED :
199109
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C11-H12-N2-O3
MOLECULAR WEIGHT :
220.25

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 69,523,1973
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 69,523,1973
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 69,523,1973

Safety Information

[ Hazard Codes ]:
Xn,Xi

[ Risk Phrases ]:
20/21-20/21/22-36/37/38-65

[ Safety Phrases ]:
26-36

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 5-Benzyloxy-Nα-benzyloxycarbonyl-D-tryptophan

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 3-((4-bromobenzyl)thio)-7-phenyl-6,7-dihydro-5H-imidazo[2,1-c][1,2,4]triazole
  • 2-(2,4,6-Trichlorophenyl)propan-2-amine
  • 2-(2-Aminophenoxy)-N-methyl-N-phenylacetamide
  • 2,6-Dichloro-3-fluoro-5-(piperidin-3-yl)pyridine
  • 4-bromo-N-(4-((4-(ethylamino)-6-methylpyrimidin-2-yl)amino)phenyl)benzenesulfonamide
  • 5-Bromo-2-chloro-4-(piperidin-3-yl)pyridine
  • N-(4-((4-(ethylamino)-6-methylpyrimidin-2-yl)amino)phenyl)-3-methylbenzenesulfonamide
  • 5-Chloro-2-fluoro-3-(piperidin-3-yl)pyridine
  • N-(4-((4-(ethylamino)-6-methylpyrimidin-2-yl)amino)phenyl)-2-fluorobenzenesulfonamide
  • 4-(2-Aminopropan-2-yl)-2-bromo-6-methoxyphenol
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