BTA-1

Names

[ CAS No. ]:
439858-28-3

[ Name ]:
BTA-1

[Synonym ]:
2-(4'-Methylaminophenyl)benzothiazole
BTA-1
Benzo-Thiazole-Aniline-1-Methyl

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₄H₁₂N₂S

[ Molecular Weight ]:
240.32300

[ Exact Mass ]:
240.07200

[ PSA ]:
53.16000

[ LogP ]:
4.07800

[ Storage condition ]:
2-8℃

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2934200090

Customs

[ HS Code ]: 2934200090

[ Summary ]:
2934200090. other compounds containing in the structure a benzothiazole ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Microglia constitute a barrier that prevents neurotoxic protofibrillar Aβ42 hotspots around plaques.

Nat. Commun. 6 , 6176, (2015)

In Alzheimer's disease (AD), β-amyloid (Aβ) plaques are tightly enveloped by microglia processes, but the significance of this phenomenon is unknown. Here we show that microglia constitute a barrier w...

The binding of 2-(4'-methylaminophenyl)benzothiazole to postmortem brain homogenates is dominated by the amyloid component.

J. Neurosci. 23 , 2086-2092, (2003)

2-(4'-methylaminophenyl)benzothiazole (BTA-1) is an uncharged derivative of thioflavin-T that has high affinity for Abeta fibrils and shows very good brain entry and clearance. In this study, we asked...

A lipophilic thioflavin-T derivative for positron emission tomography (PET) imaging of amyloid in brain.

Bioorg. Med. Chem. Lett. 12 , 295-298, (2002)

The synthesis of a new lipophilic thioflavin-T analogue (2-[4' -(methylamino)phenyl]benzothiazole, 6) with high affinity for amyloid is reported. Intravenous injection of [(11)C]-labeled 6 in control ...

BTA-1
6-OH-BTA-1
1H-Indole-3-ethanamine,N,bta,bta,1-tetramethyl-(9CI)
1-Naphthaleneethylamine,1,2-dihydro-N,N,bta,1-tetramethyl-(8CI)
1H-Benzotriazole
-bta--Alanine,N-(aminodiiminoethyl)- (9CI)
Methyl 6-{[(benzyloxy)carbonyl]amino}-2-chloro-5-methoxypyrimidine-4-carboxylate
(2S)-2-{[(benzyloxy)carbonyl]amino}-3-(3-chloro-2-fluorophenyl)propanoic acid
tert-butyl N-(2-bromoprop-2-en-1-yl)-N-[(4-chlorophenyl)methyl]carbamate
Ethyl 2-{[(tert-butoxy)carbonyl](prop-2-en-1-yl)amino}-4-(chloromethyl)-1,3-thiazole-5-carboxylate
Ethyl 2-{[(tert-butoxy)carbonyl](cyclopropyl)amino}-4-(chloromethyl)-1,3-thiazole-5-carboxylate
tert-butyl N-{8-iodopyrazolo[1,5-a][1,3,5]triazin-4-yl}carbamate
benzyl N-[5-chloro-3-(chlorosulfonyl)pyridin-2-yl]carbamate
benzyl N-(3-bromo-4-cyano-5-methoxyphenyl)carbamate
benzyl N-{2-cyano-8-oxaspiro[4.5]decan-1-yl}carbamate
tert-butyl N-methyl-N-{[3-(sulfamoylmethyl)phenyl]methyl}carbamate

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