Methoxymethyldiphenylphosphine oxide

Suppliers

Names

[ Name ]:
Methoxymethyldiphenylphosphine oxide

[Synonym ]:
(Methoxymethyl)(diphenyl)phosphine oxide
MFCD00015451
(Methoxymethyl)(diphenyl)phosphan-oxid
Methoxymethyldiphenylphosphine oxide
EINECS 224-704-4
Phosphorane, (methoxymethyl)diphenyl-, oxide
[methoxymethyl(phenyl)phosphoryl]benzene
Diphenyl(methoxymethyl)phosphine Oxide
Methoxymethyl(diphenyl)phosphine Oxide
(Methoxymethyl)diphenylphosphine oxide
(Methoxymethyl)(diphenyl)phosphane oxide

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
334.7±25.0 °C at 760 mmHg

[ Melting Point ]:
115-117ºC

[ Molecular Formula ]:
C₁₄H₁₅O₂P

[ Molecular Weight ]:
246.242

[ Flash Point ]:
170.0±43.5 °C

[ Exact Mass ]:
246.080963

[ PSA ]:
36.11000

[ LogP ]:
1.59

[ Appearance of Characters ]:
Crystalline Powder | White to pale yellow

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.556

[ Water Solubility ]:
methylene chloride: 0.1 g/mL, clear

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SZ0199360

CHEMICAL NAME :: Phosphine oxide, diphenyl(methoxymethyl)-

CAS REGISTRY NUMBER :: 4455-77-0

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C14-H15-O2-P

MOLECULAR WEIGHT :: 246.26

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: KHFZAN Khimiko-Farmatsevticheskii Zhurnal. Chemical Pharmaceutical Journal. For English translation, see PCJOAU. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1967- Volume(issue)/page/year: 24(4),22,1990

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R22

[ Safety Phrases ]:
S22-S36/37

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
SZ0199360

[ HS Code ]:
2919900090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Chlorodiphenylphosphine
2-Methoxyacetic acid
Chloromethyl methyl ether
Triphenylphosphine
Diphenylphosphine oxide
(methoxymethyl)triphenylphosphanium bromide
dimethoxymethane
lithium diphenylphosphide
methoxymethyl-triphenyl-phosphonium cation
(Methoxymethyl)triphenylphosphonium chloride

DownStream

dibutylphosphorylbenzene
[butyl(phenyl)phosphoryl]benzene
2-METHOXYACETOPHENONE
Triphenylphosphine oxide
methyldiphenylphosphine oxide
(DIPHENYLPHOSPHORYL)METHANOL
methoxymethyl(diphenyl)phosphane
[1-methoxyethyl(phenyl)phosphoryl]benzene

Customs

[ HS Code ]: 2919900090

[ Summary ]:
2919900090 other phosphoric esters and their salts, including lactophosphates; their halogenated, sulphonated, nitrated or nitrosated derivatives。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0%

Articles

C.E. Earnshaw et al.

J. Chem. Soc. Perkin Trans. I , 3099, (1979)

M. Bertrand et al.

J. Chem. Soc. Chem. Commun. , 529, (1979)

H. Magari et al.

Chem. Lett. , 1143, (1982)