N-(2-Hydroxyethyl)-1,3-propanediamine

Suppliers

Names

[ CAS No. ]:
4461-39-6

[ Name ]:
N-(2-Hydroxyethyl)-1,3-propanediamine

[Synonym ]:
2-[(3-Aminopropyl)amino]ethanol
Ethanol, 2-[(3-aminopropyl)amino]-
MFCD00025617
N-(2-Hydroxyethyl)-1,3-Propanediamine
1,3-DIAMINO-N-(2-HYDROXYETHYL)-PROPANE
2-((3-Aminopropyl)amino)ethanol
EINECS 224-718-0

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
240.7±15.0 °C at 760 mmHg

[ Melting Point ]:
15-19 °C

[ Molecular Formula ]:
C5H14N2O

[ Molecular Weight ]:
118.177

[ Flash Point ]:
99.4±20.4 °C

[ Exact Mass ]:
118.110611

[ PSA ]:
58.28000

[ LogP ]:
-1.32

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.472

[ Water Solubility ]:
miscible

MSDS

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
C:Corrosive;

[ Risk Phrases ]:
R35

[ Safety Phrases ]:
S26-S36/37/39-S45

[ RIDADR ]:
UN 2735 8/PG 3

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
8

[ HS Code ]:
29221980

Synthetic Route

Precursor & DownStream

Precursor

  • 3-[(2-Hydroxyethyl)amino]propiononitrile
  • ETHYLENE OXIDE
  • 1,3-Diaminopropane
  • Azetidine
  • 2-Aminoethanol

DownStream

  • Homopiperazine
  • N-(2-Bromoethyl)-1,3-propanediamine dihydrobromide
  • 2-[[3-[(6-Chloro-2-methoxyacridin-9-yl)amino]propyl]amino]ethanol
  • Ethanol,2-[[3-[(7-chloro-4-quinolinyl)amino]propyl]amino]-
  • 1H-1,4-Diazepine,hexahydro-1,4-bis(phenylsulfonyl)-

Customs

[ HS Code ]: 2922199090

[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Polymeric nanoparticles for nonviral gene therapy extend brain tumor survival in vivo.

ACS Nano 9(2) , 1236-49, (2015)

Biodegradable polymeric nanoparticles have the potential to be safer alternatives to viruses for gene delivery; however, their use has been limited by poor efficacy in vivo. In this work, we synthesiz...

Amylo-1,6-glucosidase/4-alpha-glucanotransferase: use of reversible substrate model inhibitors to study the binding and active sites of rabbit muscle debranching enzyme.

Biochemistry 16 , 3978, (1977)

Synthetic poly(ester amine) and poly(amido amine) nanoparticles for efficient DNA and siRNA delivery to human endothelial cells.

Int. J. Nanomedicine 6 , 3309-22, (2012)

Biodegradable poly(ester amine) (PEA)-based and poly(amido amine) (PAA)-based nanoparticles were developed for efficient in vitro siRNA delivery to human umbilical vein endothelial cells (HUVECs). The...


More Articles


Related Compounds

  • N-(2-hydroxyethyl)-1-(3-nitrophenyl)methanimine oxide
  • N-(3-Aminopropyl)diethanolamine
  • 5-Pyrimidinecarboxamide,1,2,3,4-tetrahydro-N-(2-hydroxyethyl)-1,3-dimethyl-2,4-dioxo-
  • 2-Amino-Benzothiazole-6-carboxylic acid (2-hydroxy-Ethyl)-Amide
  • 3-(2-Hydroxyethyl)-2-oxazolidinone
  • N-(2-phenylethyl)-1,3-propanediamine
  • 1-Cyclopentyl-2-(6-methylpiperidin-2-yl)ethan-1-one
  • 4-Chloro-5-(difluoromethyl)-2-methylnicotinaldehyde
  • 5-(Difluoromethyl)-3-methoxy-2-methylpyridin-4-amine
  • tert-Butyl (5-fluoro-4-phenylpyridin-3-yl)carbamate
  • Tert-butyl (4-butyryl-6-chloropyridin-3-yl)carbamate
  • (5-amino-2-methyl-4-pyridinyl)cyclopropylMethanone
  • Tert-butyl (6-chloro-4-(1-hydroxybutyl)pyridin-3-yl)carbamate
  • 6-Fluoro-4-phenyl-3-pyridinamine
  • 5-[2-(3-chloropropyl)-1,3-dioxolan-2-yl]-4-Pyridazinamine
  • 6-Fluoro-2,4-diphenyl-3-pyridinamine