N-(2-Hydroxyethyl)-1,3-propanediamine

N-(2-Hydroxyethyl)-1,3-propanediamine Structure
N-(2-Hydroxyethyl)-1,3-propanediamine structure
Common Name N-(2-Hydroxyethyl)-1,3-propanediamine
CAS Number 4461-39-6 Molecular Weight 118.177
Density 1.0±0.1 g/cm3 Boiling Point 240.7±15.0 °C at 760 mmHg
Molecular Formula C5H14N2O Melting Point 15-19 °C
MSDS Chinese USA Flash Point 99.4±20.4 °C
Symbol GHS05
GHS05
Signal Word Danger

Polymeric nanoparticles for nonviral gene therapy extend brain tumor survival in vivo.

ACS Nano 9(2) , 1236-49, (2015)

Biodegradable polymeric nanoparticles have the potential to be safer alternatives to viruses for gene delivery; however, their use has been limited by poor efficacy in vivo. In this work, we synthesize and characterize polymeric gene delivery nanoparticles an...

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Synthetic poly(ester amine) and poly(amido amine) nanoparticles for efficient DNA and siRNA delivery to human endothelial cells.

Int. J. Nanomedicine 6 , 3309-22, (2012)

Biodegradable poly(ester amine) (PEA)-based and poly(amido amine) (PAA)-based nanoparticles were developed for efficient in vitro siRNA delivery to human umbilical vein endothelial cells (HUVECs). They were screened, characterized, and compared with tradition...