Benzol-1,2,4,5-tetramintetrahydrochlorid

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Names

[ Name ]:
Benzol-1,2,4,5-tetramintetrahydrochlorid

[Synonym ]:
Benzene-1,2,4,5-tetrayltetraamine tetrahydrochloride
1,2,4,5-tetraaminobenzene tetra-hydrochloride
1,2,4,5-Benzenetetramine, tetrahydrochloride
Benzene-1,2,4,5-tetramine tetrahydrochloride
EINECS 224-822-6
MFCD00012970
Benzol-1,2,4,5-tetramintetrahydrochlorid
1,2,4,5-BENZENETETRAMINE TETRAHYDROCHLORIDE
1,2,4,5-Benzenetetramine, hydrochloride (1:4)
Benzene-1,2,4,5-tetraamine tetrahydrochloride
1,2,4,5-Benzenetetraamine tetrahydrochloride
1,2,4,5-tetraaminobenzene tetahydrochloride
Y15

Chemical & Physical Properties

[ Boiling Point ]:
400.9ºC at 760mmHg

[ Melting Point ]:
≥300ºC(lit.)

[ Molecular Formula ]:
C₆H₁₄Cl₄N₄

[ Molecular Weight ]:
284.014

[ Flash Point ]:
233.6ºC

[ Exact Mass ]:
281.997253

[ PSA ]:
104.08000

[ LogP ]:
5.54820

[ Index of Refraction ]:
1.827

[ Storage condition ]:
Desiccate at RT

[ Water Solubility ]:
H2O: soluble20mg/mL, clear

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2921590090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2921590090

[ Summary ]:
2921590090. other aromatic polyamines and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Down-regulation of ALDH1A3, CD44 or MDR1 sensitizes resistant cancer cells to FAK autophosphorylation inhibitor Y15.

J. Cancer Res. Clin. Oncol. 141 , 1613-31, (2015)

Focal adhesion kinase is an important survival signal in cancer. Recently, we demonstrated that the autophosphorylation inhibitor of FAK, Y15, effectively inhibited cancer cell growth. We detected man...

FAK is a critical regulator of neuroblastoma liver metastasis.

Oncotarget 3 , 1576-87, (2013)

Neuroblastomas express increased levels of gastrin-releasing peptide receptor (GRP-R). However, the exact molecular mechanisms involved in GRP-R-mediated cell signaling in neuroblastoma growth and met...

CEACAM6 promotes tumor angiogenesis and vasculogenic mimicry in gastric cancer via FAK signaling.

Biochim. Biophys. Acta 1852(5) , 1020-8, (2015)

CEACAM6 is a member of glycosylphosphatidylinositol-linked immunoglobulin superfamily that is implicated in a variety of human cancers. In our previous study, we reported that CEACAM6 was overexpresse...