2-Phenylacetophenone

Names

[ CAS No. ]:
451-40-1

[ Name ]:
2-Phenylacetophenone

[Synonym ]:
Ethanone, 1,2-diphenyl-
Benzoin,deoxy
1,2-Diphenylethanone
MFCD00003081
benzyl phenyl ketone
1,2-diphenyl-ethanone
DESOXYBENZOIN
EINECS 207-193-2
Deoxybenzoin
Desoxybenzoine

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
320.6±11.0 °C at 760 mmHg

[ Melting Point ]:
54-55 °C(lit.)

[ Molecular Formula ]:
C₁₄H₁₂O

[ Molecular Weight ]:
196.245

[ Flash Point ]:
137.0±14.2 °C

[ Exact Mass ]:
196.088821

[ PSA ]:
17.07000

[ LogP ]:
3.18

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.584

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
methanol: 0.1 g/mL, clear

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AM9662500

CHEMICAL NAME :: Acetophenone, 2-phenyl-

CAS REGISTRY NUMBER :: 451-40-1

BEILSTEIN REFERENCE NO. :: 1072876

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C14-H12-O

MOLECULAR WEIGHT :: 196.26

WISWESSER LINE NOTATION :: RV1R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 320 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#03836

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
AM9662500

[ HS Code ]:
29143900

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Benzil
Phenylacetyl chloride
benzene
Oxirane, 2,3-diphenyl-,(2R,3S)-rel-
Benzyl cyanide
Phenylboronic acid
Chlorobenzene
Acetophenone
2-methylsulfanyl-1,2-diphenyl-ethanone
Phenyl ethyl ketone

DownStream

2-Methyl-4,5-diphenylthiazole
methyl diphenylacetate
1,1,2-trimethoxy-1,2-diphenylethane
4,4'-azobisbenzoic acid
Methyl benzoin
2-iodo-1,2-diphenylethanone
4-BENZYLBIPHENYL
Ethyl benzoate
1,1,1-Trifluoro-3-phenylacetone
Benzohydroxamic acid

Customs

[ HS Code ]: 2914399090

[ Summary ]:
2914399090. other aromatic ketones without other oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

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