4-Fluoro-3-nitrobenzoic acid

Suppliers

Names

[ CAS No. ]:
453-71-4

[ Name ]:
4-Fluoro-3-nitrobenzoic acid

[Synonym ]:
5-Carboxy-2-fluoronitrobenzene
4-fluoro-5-nitrobenzoic acid
3-Nitro-4-fluorobenzoic acid
MFCD00007058
Benzoic acid, 4-fluoro-3-nitro-
4-Fluoro-3-nitrobenzoic acid
p-Fluoro-3-nitrobenzoic acid
p-fluoro-m-nitrobenzoic acid
WNR BF EVQ
4-fluoro-3-nitro benzoic acid
EINECS 207-221-3

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
356.9±27.0 °C at 760 mmHg

[ Melting Point ]:
123-126 °C(lit.)

[ Molecular Formula ]:
C7H4FNO4

[ Molecular Weight ]:
185.109

[ Flash Point ]:
169.6±23.7 °C

[ Exact Mass ]:
185.012436

[ PSA ]:
83.12000

[ LogP ]:
1.69

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.588

[ Storage condition ]:
Refrigerator

[ Water Solubility ]:
insoluble

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R22;R36/37/38

[ Safety Phrases ]:
S26-S36-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ HS Code ]:
2916399090

Synthetic Route

Precursor & DownStream

Precursor

  • 4-Fluorobenzoic acid
  • 4-Fluoro-3-nitrotoluene
  • 4-Fluorobenzaldehyde
  • 4-Fluorotoluene
  • nitric acid

DownStream

  • METHYL 3-AMINO-4-(ISOPROPYLAMINO)BENZOATE
  • Methyl 4-fluoro-3-nitrobenzoate
  • 4-(2-hydroxyethylamino)-3-nitrobenzoic acid
  • Ethyl 4-fluoro-3-nitrobenzoate
  • Ethyl 3-amino-4-fluorobenzoate
  • 4-(Methylamino)-3-nitrobenzoic acid
  • 4-(Cyclohexylamino)-3-nitrobenzoic acid
  • 2-Methyl-1-phenyl-1H-benzo[d]imidazole-5-carboxylic acid
  • 3-AMINO-4-FLUOROBENZOIC ACID HYDROCHLORIDE
  • Methyl 3-amino-4-fluorobenzoate

Customs

[ HS Code ]: 2916399090

[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Solid phase synthesis of functionalized biaryl ethers: versatile scaffolds for combinatorial chemistry.

Mol. Divers. 3(2) , 117-20, (1997)

4-Fluoro-3-nitrobenzoic acid attached to a solid support was shown to react under mild conditions with a wide range of functionalized phenols to yield, after cleavage, the corresponding biaryl ethers ...

Combinatorial synthesis of biheterocyclic benzimidazoles by microwave irradiation.

Comb. Chem. High Throughput Screen 7(3) , 251-5, (2004)

Liquid phasel synthesis of biheterocyclic benzimidazoles by controlled microwave irradiation was investigated. Polymer immobilized o-phenylenediamines was synthesized under microwave irradiation. The ...

Reagents for the preparation of chromophorically labeled polyethylene glycol-protein conjugates.

Anal. Biochem. 210(2) , 258-61, (1993)

We have developed a new class of reagents (2) for the covalent attachment of polyethylene glycol to proteins. These reagents (2) are the monomethoxypolyethylene glycol esters of 4-fluoro-3-nitrobenzoi...


More Articles


Related Compounds

  • 4-Fluoro-3-nitrobenzoic acid ethyl ester
  • 4-Fluoro-3-nitrobenzoic acid benzyl ester
  • 4-Fluoro-3-nitrobenzoic acid methyl ester
  • 4-fluoro-3-nitrobenzoic acid tert-butyl ester
  • 4-fluoro-2-methyl-3-nitrobenzoic acid
  • 4-(4-fluoro-3-methoxyphenyl)-2-nitrobenzoic acid