4-Fluoro-3-nitrobenzoic acid

Modify Date: 2024-01-02 18:12:44

4-Fluoro-3-nitrobenzoic acid Structure
4-Fluoro-3-nitrobenzoic acid structure
Common Name 4-Fluoro-3-nitrobenzoic acid
CAS Number 453-71-4 Molecular Weight 185.109
Density 1.6±0.1 g/cm3 Boiling Point 356.9±27.0 °C at 760 mmHg
Molecular Formula C7H4FNO4 Melting Point 123-126 °C(lit.)
MSDS Chinese USA Flash Point 169.6±23.7 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 4-Fluoro-3-nitrobenzoic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 356.9±27.0 °C at 760 mmHg
Melting Point 123-126 °C(lit.)
Molecular Formula C7H4FNO4
Molecular Weight 185.109
Flash Point 169.6±23.7 °C
Exact Mass 185.012436
PSA 83.12000
LogP 1.69
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.588
Storage condition Refrigerator
Water Solubility insoluble

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn:Harmful;
Risk Phrases R22;R36/37/38
Safety Phrases S26-S36-S24/25
RIDADR NONH for all modes of transport
WGK Germany 2
HS Code 2916399090

 Synthetic Route

~88%

4-Fluoro-3-nitrobenzoic acid Structure

4-Fluoro-3-nitr...

CAS#:453-71-4

Literature: Bleicher, Konrad; Christ, Andreas D.; Martin, Rainer E.; Mohr, Peter Patent: US2008/249101 A1, 2008 ; Location in patent: Page/Page column 20 ;

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4-Fluoro-3-nitrobenzoic acid Structure

4-Fluoro-3-nitr...

CAS#:453-71-4

Literature: LES LABORATOIRES SERVIER Patent: US2010/9974 A1, 2010 ; Location in patent: Page/Page column 22-23 ;

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4-Fluoro-3-nitrobenzoic acid Structure

4-Fluoro-3-nitr...

CAS#:453-71-4

Literature: Oelschlaeger,H.; Schmersahl,P. Archiv der Pharmazie und Berichte der Deutschen Pharmazeutischen Gesellschaft, 1963 , vol. 296, p. 324 - 336

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4-Fluoro-3-nitrobenzoic acid Structure

4-Fluoro-3-nitr...

CAS#:453-71-4

Literature: Slothouwer Recueil des Travaux Chimiques des Pays-Bas, 1914 , vol. 33, p. 336

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4-Fluoro-3-nitrobenzoic acid Structure

4-Fluoro-3-nitr...

CAS#:453-71-4

Literature: Slothouwer Recueil des Travaux Chimiques des Pays-Bas, 1914 , vol. 33, p. 336

~%

4-Fluoro-3-nitrobenzoic acid Structure

4-Fluoro-3-nitr...

CAS#:453-71-4

Literature: Rouche Bulletin de la Classe des Sciences, Academie Royale de Belgique, 1921 , vol. <5> 7, p. 536 Chem. Zentralbl., 1922 , vol. 93, # I p. 22

 Customs

HS Code 2916399090
Summary 2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Articles7

More Articles
Solid phase synthesis of functionalized biaryl ethers: versatile scaffolds for combinatorial chemistry.

Mol. Divers. 3(2) , 117-20, (1997)

4-Fluoro-3-nitrobenzoic acid attached to a solid support was shown to react under mild conditions with a wide range of functionalized phenols to yield, after cleavage, the corresponding biaryl ethers ...

Combinatorial synthesis of biheterocyclic benzimidazoles by microwave irradiation.

Comb. Chem. High Throughput Screen 7(3) , 251-5, (2004)

Liquid phasel synthesis of biheterocyclic benzimidazoles by controlled microwave irradiation was investigated. Polymer immobilized o-phenylenediamines was synthesized under microwave irradiation. The ...

Reagents for the preparation of chromophorically labeled polyethylene glycol-protein conjugates.

Anal. Biochem. 210(2) , 258-61, (1993)

We have developed a new class of reagents (2) for the covalent attachment of polyethylene glycol to proteins. These reagents (2) are the monomethoxypolyethylene glycol esters of 4-fluoro-3-nitrobenzoi...

 Synonyms

5-Carboxy-2-fluoronitrobenzene
4-fluoro-5-nitrobenzoic acid
3-Nitro-4-fluorobenzoic acid
MFCD00007058
Benzoic acid, 4-fluoro-3-nitro-
4-Fluoro-3-nitrobenzoic acid
p-Fluoro-3-nitrobenzoic acid
p-fluoro-m-nitrobenzoic acid
WNR BF EVQ
4-fluoro-3-nitro benzoic acid
EINECS 207-221-3
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